Cerebral hemorrhage: pathophysiology, treatment, and future directions

J Magid-Bernstein, R Girard, S Polster… - Circulation …, 2022 - Am Heart Assoc
Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and
mortality. This review article focuses on the epidemiology, cause, mechanisms of injury …

[HTML][HTML] Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease

Y Inoue, F Shue, G Bu, T Kanekiyo - Molecular neurodegeneration, 2023 - Springer
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

[HTML][HTML] Vascular cognitive impairment (VCI)

T Rundek, M Tolea, T Ariko, EA Fagerli, CJ Camargo - Neurotherapeutics, 2023 - Elsevier
Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …

Clinical significance of magnetic resonance imaging markers of vascular brain injury: a systematic review and meta-analysis

S Debette, S Schilling, MG Duperron… - JAMA …, 2019 - jamanetwork.com
Importance Covert vascular brain injury (VBI) is highly prevalent in community-dwelling
older persons, but its clinical and therapeutic implications are debated. Objective To better …

Vascular cognitive impairment

M Dichgans, D Leys - Circulation research, 2017 - Am Heart Assoc
Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.
Vascular cognitive impairment refers to all forms of cognitive disorder associated with …

Perivascular spaces, glymphatic dysfunction, and small vessel disease

H Mestre, S Kostrikov, RI Mehta… - Clinical …, 2017 - portlandpress.com
Cerebral small vessel diseases (SVDs) range broadly in etiology but share remarkably
overlapping pathology. Features of SVD including enlarged perivascular spaces (EPVS) …

Association of cerebral microbleeds with cognitive decline and dementia

S Akoudad, FJ Wolters, A Viswanathan… - JAMA …, 2016 - jamanetwork.com
Importance Cerebral microbleeds are hypothesized downstream markers of brain damage
caused by vascular and amyloid pathologic mechanisms. To date, whether their presence is …

Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke …

PB Gorelick, A Scuteri, SE Black, C DeCarli… - stroke, 2011 - Am Heart Assoc
Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis

S Debette, HS Markus - Bmj, 2010 - bmj.com
Objectives To review the evidence for an association of white matter hyperintensities with
risk of stroke, cognitive decline, dementia, and death. Design Systematic review and meta …

Intracerebral haemorrhage

AI Qureshi, AD Mendelow, DF Hanley - The Lancet, 2009 - thelancet.com
Intracerebral haemorrhage is an important public health problem leading to high rates of
death and disability in adults. Although the number of hospital admissions for intracerebral …