The extracellular matrix and the immune system: A mutually dependent relationship
For decades, immunologists have studied the role of circulating immune cells in host
protection, with a more recent appreciation of immune cells resident within the tissue …
protection, with a more recent appreciation of immune cells resident within the tissue …
The role of goblet cells and mucus in intestinal homeostasis
JK Gustafsson, MEV Johansson - Nature reviews Gastroenterology & …, 2022 - nature.com
The intestinal tract faces numerous challenges that require several layers of defence. The
tight epithelium forms a physical barrier that is further protected by a mucus layer, which …
tight epithelium forms a physical barrier that is further protected by a mucus layer, which …
Carbohydrate-active enzymes (CAZymes) in the gut microbiome
JF Wardman, RK Bains, P Rahfeld… - Nature Reviews …, 2022 - nature.com
The 1013–1014 microorganisms present in the human gut (collectively known as the human
gut microbiota) dedicate substantial percentages of their genomes to the degradation and …
gut microbiota) dedicate substantial percentages of their genomes to the degradation and …
Intestinal mucus and their glycans: A habitat for thriving microbiota
AS Luis, GC Hansson - Cell Host & Microbe, 2023 - cell.com
The colon mucus layer is organized with an inner colon mucus layer that is impenetrable to
bacteria and an outer mucus layer that is expanded to allow microbiota colonization. A major …
bacteria and an outer mucus layer that is expanded to allow microbiota colonization. A major …
The gut microbiota and its biogeography
G McCallum, C Tropini - Nature Reviews Microbiology, 2024 - nature.com
Biogeography is the study of species distribution and diversity within an ecosystem and is at
the core of how we understand ecosystem dynamics and interactions at the macroscale. In …
the core of how we understand ecosystem dynamics and interactions at the macroscale. In …
IL-4 and IL-13: regulators and effectors of wound repair
JE Allen - Annual review of immunology, 2023 - annualreviews.org
Type 2 immunity mediates protective responses to helminths and pathological responses to
allergens, but it also has broad roles in the maintenance of tissue integrity, including wound …
allergens, but it also has broad roles in the maintenance of tissue integrity, including wound …
Host-microbiota interaction-mediated resistance to inflammatory bowel disease in pigs
X Zhao, L Jiang, X Fang, Z Guo, X Wang, B Shi… - Microbiome, 2022 - Springer
Background Disease resistance phenotypes are associated with immune regulatory
functions and immune tolerance and have implications for both the livestock industry and …
functions and immune tolerance and have implications for both the livestock industry and …
Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria
B Shuoker, MJ Pichler, C Jin, H Sakanaka… - Nature …, 2023 - nature.com
The mucolytic human gut microbiota specialist Akkermansia muciniphila is proposed to
boost mucin-secretion by the host, thereby being a key player in mucus turnover. Mucin …
boost mucin-secretion by the host, thereby being a key player in mucus turnover. Mucin …
SulfAtlas, the sulfatase database: state of the art and new developments
Abstract SulfAtlas (https://sulfatlas. sb-roscoff. fr/) is a knowledge-based resource dedicated
to a sequence-based classification of sulfatases. Currently four sulfatase families exist (S1 …
to a sequence-based classification of sulfatases. Currently four sulfatase families exist (S1 …
Genome-centric investigation of bile acid metabolizing microbiota of dairy cows and associated diet-induced functional implications
Although the importance of bile acid (BA)-related microbial strains and enzymes is
increasingly recognized for monogastric animals, a lack of knowledge about BA metabolism …
increasingly recognized for monogastric animals, a lack of knowledge about BA metabolism …