Immune response in the asthmatic respiratory tract is mainly driven by CD4+ T helper (Th)
cells, represented by Th1, Th2, and Th17 cells, especially Th2 cells. Asthma is a …

HIF is a transcription factor that plays an essential role in the cellular response to low
oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In …

2-Hydroxyglutarate (2-HG) is structurally similar to α-ketoglutarate (α-KG), which is an
intermediate product of the tricarboxylic acid (TCA) cycle; it can be generated by reducing …

Airway hyperresponsiveness (AHR) is characterized by excessive bronchoconstriction in
response to nonspecific stimuli, thereby leading to airway stenosis and increased airway …

Background The associations between fine and coarse particulate matter (PM2. 5 and PM2.
5–10) air pollution and hospital admissions for full-spectrum respiratory diseases were …

Background Dysregulation of long noncoding RNAs (lncRNAs) is associated with a variety
of human diseases; however, whether they have a role in childhood asthma is unknown …

The health consequences of climate change are being increasingly recognized. Herein, the
climate change hypothesis is put forth as a substantial contributor to the growing global …

Alkyl organophosphate flame retardants (OPFRs), tri-n-butyl phosphate (TnBP) and tris (2-
butoxyethyl) phosphate (TBOEP), are ubiquitously detected in indoor and outdoor …

The aryl hydrocarbon receptor (AhR) is a widely studied ligand-activated cytosolic
transcriptional factor that has been associated with the initiation and progression of various …

There is limited evidence regarding the relationship between air pollution and pediatric
asthma in developing countries. This study aimed to investigate the association between …