Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment

RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …

Application of deep learning in detecting neurological disorders from magnetic resonance images: a survey on the detection of Alzheimer's disease, Parkinson's …

MBT Noor, NZ Zenia, MS Kaiser, SA Mamun… - Brain informatics, 2020 - Springer
Neuroimaging, in particular magnetic resonance imaging (MRI), has been playing an
important role in understanding brain functionalities and its disorders during the last couple …

[HTML][HTML] Computational approaches to explainable artificial intelligence: advances in theory, applications and trends

JM Górriz, I Álvarez-Illán, A Álvarez-Marquina, JE Arco… - Information …, 2023 - Elsevier
Deep Learning (DL), a groundbreaking branch of Machine Learning (ML), has emerged as a
driving force in both theoretical and applied Artificial Intelligence (AI). DL algorithms, rooted …

Artificial intelligence in psychiatry research, diagnosis, and therapy

J Sun, QX Dong, SW Wang, YB Zheng, XX Liu… - Asian Journal of …, 2023 - Elsevier
Psychiatric disorders are now responsible for the largest proportion of the global burden of
disease, and even more challenges have been seen during the COVID-19 pandemic …

Bias in machine learning models can be significantly mitigated by careful training: Evidence from neuroimaging studies

R Wang, P Chaudhari… - Proceedings of the …, 2023 - National Acad Sciences
Despite the great promise that machine learning has offered in many fields of medicine, it
has also raised concerns about potential biases and poor generalization across genders …

[HTML][HTML] NeuroMark: An automated and adaptive ICA based pipeline to identify reproducible fMRI markers of brain disorders

Y Du, Z Fu, J Sui, S Gao, Y Xing, D Lin, M Salman… - NeuroImage: Clinical, 2020 - Elsevier
Many mental illnesses share overlapping or similar clinical symptoms, confounding the
diagnosis. It is important to systematically characterize the degree to which unique and …

[HTML][HTML] Schizophrenia: The new etiological synthesis

MJ Rantala, S Luoto, JI Borráz-León, I Krams - … & Biobehavioral Reviews, 2022 - Elsevier
Schizophrenia has been an evolutionary paradox: it has high heritability, but it is associated
with decreased reproductive success. The causal genetic variants underlying schizophrenia …

[HTML][HTML] Methodological and quality flaws in the use of artificial intelligence in mental health research: systematic review

R Tornero-Costa, A Martinez-Millana… - JMIR Mental …, 2023 - mental.jmir.org
Background: Artificial intelligence (AI) is giving rise to a revolution in medicine and health
care. Mental health conditions are highly prevalent in many countries, and the COVID-19 …

A deep learning framework identifies dimensional representations of Alzheimer's Disease from brain structure

Z Yang, IM Nasrallah, H Shou, J Wen, J Doshi… - Nature …, 2021 - nature.com
Heterogeneity of brain diseases is a challenge for precision diagnosis/prognosis. We
describe and validate Smile-GAN (SeMI-supervised cLustEring-Generative Adversarial …

Subcortical volumetric alterations in four major psychiatric disorders: a mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification

N Okada, M Fukunaga, K Miura, K Nemoto… - Molecular …, 2023 - nature.com
Differential diagnosis is sometimes difficult in practical psychiatric settings, in terms of using
the current diagnostic system based on presenting symptoms and signs. The creation of a …