Brain mechanisms underlying apathy
The past few decades have seen growing interest in the neuropsychiatric syndrome of
apathy, conceptualised as a loss of motivation manifesting as a reduction of goal-directed …
apathy, conceptualised as a loss of motivation manifesting as a reduction of goal-directed …
[HTML][HTML] The neural basis of effort valuation: A meta-analysis of functional magnetic resonance imaging studies
Choosing how much effort to expend is critical for everyday decisions. While several
neuroimaging studies have examined effort-based decision-making, results have been …
neuroimaging studies have examined effort-based decision-making, results have been …
History of winning remodels thalamo-PFC circuit to reinforce social dominance
Mental strength and history of winning play an important role in the determination of social
dominance. However, the neural circuits mediating these intrinsic and extrinsic factors have …
dominance. However, the neural circuits mediating these intrinsic and extrinsic factors have …
Dynamics of a disinhibitory prefrontal microcircuit in controlling social competition
Social competition plays a pivotal role in determining individuals' social status. While the
dorsomedial prefrontal cortex (dmPFC) is essential in regulating social competition, it …
dorsomedial prefrontal cortex (dmPFC) is essential in regulating social competition, it …
Dopamine, effort-based choice, and behavioral economics: basic and translational research
Operant behavior is not only regulated by factors related to the quality or quantity of
reinforcement, but also by the work requirements inherent in performing instrumental …
reinforcement, but also by the work requirements inherent in performing instrumental …
Distinct effects of apathy and dopamine on effort-based decision-making in Parkinson's disease
Effort-based decision-making is a cognitive process crucial to normal motivated behaviour.
Apathy is a common and disabling complication of Parkinson's disease, but its aetiology …
Apathy is a common and disabling complication of Parkinson's disease, but its aetiology …
BehaviorDEPOT is a simple, flexible tool for automated behavioral detection based on markerless pose tracking
Quantitative descriptions of animal behavior are essential to study the neural substrates of
cognitive and emotional processes. Analyses of naturalistic behaviors are often performed …
cognitive and emotional processes. Analyses of naturalistic behaviors are often performed …
Advances in understanding neural mechanisms of social dominance
Dominance hierarchy profoundly impacts social animals' survival, physical and mental
health and reproductive success. As the measurements of dominance hierarchy in rodents …
health and reproductive success. As the measurements of dominance hierarchy in rodents …
The psychopharmacology of effort-related decision making: dopamine, adenosine, and insights into the neurochemistry of motivation
Effort-based decision making is studied using tasks that offer choices between high-effort
options leading to more highly valued reinforcers versus low-effort/low-reward options …
options leading to more highly valued reinforcers versus low-effort/low-reward options …
Obesity and dietary fat influence dopamine neurotransmission: Exploring the convergence of metabolic state, physiological stress, and inflammation on dopaminergic …
CW Wallace, SC Fordahl - Nutrition research reviews, 2022 - cambridge.org
The aim of this review is to explore how metabolic changes induced by diets high in
saturated fat (HFD) affect nucleus accumbens (NAc) dopamine neurotransmission and food …
saturated fat (HFD) affect nucleus accumbens (NAc) dopamine neurotransmission and food …