Early life imprinting of intestinal immune tolerance and tissue homeostasis

YA Paucar Iza, CC Brown - Immunological Reviews, 2024 - Wiley Online Library
Besides its canonical role in protecting the host from pathogens, the immune system plays
an arguably equally important role in maintaining tissue homeostasis. Within barrier tissues …

[HTML][HTML] Role reversals: non-canonical roles for immune and non-immune cells in the gut

JLE Tearle, A Tang, A Vasanthakumar, KR James - Mucosal Immunology, 2024 - Elsevier
The intestine is home to an intertwined network of epithelial, immune, and neuronal cells as
well as the microbiome, with implications for immunity, systemic metabolism, and behavior …

Analysis of intestinal epithelial cell responses to Cryptosporidium highlights the temporal effects of IFN-γ on parasite restriction

RD Pardy, KA Walzer, BA Wallbank, JH Byerly… - Plos …, 2024 - journals.plos.org
The production of IFN-γ is crucial for control of multiple enteric infections, but its impact on
intestinal epithelial cells (IEC) is not well understood. Cryptosporidium parasites exclusively …

[HTML][HTML] Dietary fiber promotes antigen presentation on intestinal epithelial cells and development of small intestinal CD4+ CD8αα+ intraepithelial T cells

N Rodriguez-Marino, CJ Royer… - Mucosal …, 2024 - Elsevier
The impact of dietary fiber on intestinal T cell development is poorly understood. Here we
show that a low fiber diet reduces MHC-II antigen presentation by small intestinal epithelial …

Pathways and mechanisms of CD4+ CD8αα+ intraepithelial T cell development

C Li, D Lanasa, JH Park - Trends in Immunology, 2024 - cell.com
The mammalian small intestine epithelium harbors a peculiar population of CD4+ CD8αα+ T
cells that are derived from mature CD4+ T cells through reprogramming of lineage-specific …

[HTML][HTML] Epithelial regulation of microbiota-immune cell dynamics

BJ Didriksen, EM Eshleman, T Alenghat - Mucosal Immunology, 2024 - Elsevier
The mammalian gastrointestinal tract hosts a diverse community of trillions of
microorganisms, collectively termed the microbiota, which play a fundamental role in …

Juniperus oxycedrus L. ssp. Essential Oil Microneedles: A Promising Antimicrobial and Wound Healing Activity

B Battah, L Shbibe, O Ahmad, C Soukkarieh… - Pharmaceuticals, 2023 - mdpi.com
The use of essential oil (EO) in treating infected wounds is still challenging. A lot of effort has
been made to make such an application more convenient. Recently, microneedles (MNDs) …

Eosinophilic gastrointestinal disorders and the role for the epithelium in pathogenesis and treatment

EM Rodríguez-López, DA Hill - Current Opinion in Pediatrics, 2024 - journals.lww.com
While there has been significant progress in understanding the role of the epithelium in EoE,
further research is needed to obtain a better understanding of the mechanisms mediating …

[PDF][PDF] The effect of early microbiome modification on immune development and function in broiler chickens

A Watts - 2024 - livrepository.liverpool.ac.uk
Enteritidis (S. Enteritidis) are important global pathogens, best known for their role in human
gastroenteritis. Chickens can act as a reservoir for these pathogens, which can be …