Flavonoids as an effective sensitizer for anti-cancer therapy: Insights into multi-faceted mechanisms and applicability towards individualized patient profiles

A Liskova, M Samec, L Koklesova, A Brockmueller… - Epma Journal, 2021 - Springer
Cost-efficacy of currently applied treatments is an issue in overall cancer management
challenging healthcare and causing tremendous economic burden to societies around the …

Dietary phytochemicals in breast cancer research: anticancer effects and potential utility for effective chemoprevention

A Kapinova, P Kubatka, O Golubnitschaja… - … health and preventive …, 2018 - Springer
Cancerous tissue transformation developing usually over years or even decades of life is a
highly complex process involving strong stressors damaging DNA, chronic inflammation …

Long noncoding RNA LINC00511 contributes to breast cancer tumourigenesis and stemness by inducing the miR-185-3p/E2F1/Nanog axis

G Lu, Y Li, Y Ma, J Lu, Y Chen, Q Jiang, Q Qin… - Journal of experimental …, 2018 - Springer
Background Emerging evidence have illustrated the vital role of long noncoding RNAs
(lncRNAs) long intergenic non-protein coding RNA 00511 (LINC00511) on the human …

Flavonoids against the Warburg phenotype—Concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism

M Samec, A Liskova, L Koklesova, SM Samuel, K Zhai… - Epma Journal, 2020 - Springer
The Warburg effect is characterised by increased glucose uptake and lactate secretion in
cancer cells resulting from metabolic transformation in tumour tissue. The corresponding …

[HTML][HTML] Chemotherapeutic agents for the treatment of metastatic breast cancer: An update

M Abotaleb, P Kubatka, M Caprnda, E Varghese… - Biomedicine & …, 2018 - Elsevier
Breast cancer is the second greatest cause of death among women worldwide; it comprises
a group of heterogeneous diseases that evolves due to uncontrolled cellular growth and …

Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care

A Mazurakova, L Koklesova, M Samec, E Kudela… - EPMA Journal, 2022 - Springer
Breast cancer incidence is actually the highest one among all cancers. Overall breast cancer
management is associated with challenges considering risk assessment and predictive …

Preparation of celery essential oil-based nanoemulsion by ultrasonication and evaluation of its potential anticancer and antibacterial activity

MJ Nirmala, L Durai, V Gopakumar… - International Journal of …, 2020 - Taylor & Francis
Introduction Plants have always been a significant source of natural active components with
biological properties. Celery seed oil (extracted from Apium graveolens) has several …

Role of hedgehog signaling in breast cancer: pathogenesis and therapeutics

NA Riobo-Del Galdo, A Lara Montero, EV Wertheimer - Cells, 2019 - mdpi.com
Breast cancer (BC) is the leading cause of cancer-related mortality in women, only followed
by lung cancer. Given the importance of BC in public health, it is essential to identify …

Anticancer Activities of Thymus vulgaris L. in Experimental Breast Carcinoma In Vivo and In Vitro

P Kubatka, S Uramova, M Kello, K Kajo… - International journal of …, 2019 - mdpi.com
Naturally-occurring mixtures of phytochemicals present in plant foods are proposed to
possess tumor-suppressive activities. In this work, we aimed to evaluate the antitumor effects …

Are plant-based functional foods better choice against cancer than single phytochemicals? A critical review of current breast cancer research

A Kapinova, P Stefanicka, P Kubatka, P Zubor… - Biomedicine & …, 2017 - Elsevier
Breast cancer is the most common malignancy in women worldwide. Over 90% of all breast
cancer cases are of different 'sporadic'cell types, thus placing emphasis on the need for …