Elucidating the Architectural dynamics of MuB filaments in bacteriophage Mu DNA transposition

X Zhao, Y Gao, Q Gong, K Zhang, S Li - Nature Communications, 2024 - nature.com
MuB is a non-specific DNA-binding protein and AAA+ ATPase that significantly influences
the DNA transposition process of bacteriophage Mu, especially in target DNA selection for …

Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal

JR Fuller, PA Rice - Elife, 2017 - elifesciences.org
The transposition of bacteriophage Mu serves as a model system for understanding DDE
transposases and integrases. All available structures of these enzymes at the end of the …

Deep sequencing reveals new roles for MuB in transposition immunity and target-capture, and redefines the insular Ter region of E. coli

DM Walker, RM Harshey - Mobile DNA, 2020 - Springer
Background The target capture protein MuB is responsible for the high efficiency of phage
Mu transposition within the E. coli genome. However, some targets are off-limits, such as …

Mu Transposition in the Absence of the Target-capture Protein MuB Reveals New Roles of MuB in Target Immunity and Target Selection, and Redraws the Boundaries …

DM Walker, RM Harshey - bioRxiv, 2020 - biorxiv.org
The target capture protein MuB is responsible for the high efficiency of phage Mu
transposition within the E. coli genome. However, some targets are off-limits, such as …

DNA dynamics and irreversibility regulate Mu transposition

JR Fuller - 2016 - search.proquest.com
Transposition moves or copies specifically defined segments of DNA from one location to
another. The transposon—the mobile DNA—is delineated by sequences at each end that …