A wide range of nitric oxide (NO)-releasing materials has emerged as potential therapeutics
that exploit NO's vast biological roles. Macromolecular NO-releasing scaffolds are …

Topical and oral antibiotics are routinely used to treat acne. However, antibiotic resistance is
increasing, with many countries reporting that more than 50% of Propionibacterium acnes …

Many publications list advantages and disadvantages associated with phage therapy, which
is the use of bacterial viruses to combat populations of nuisance or pathogenic bacteria. The …

The human body is home to a variety of micro-organisms. Most of these microbial
communities reside in the gut and are referred to as gut microbiota. Over the last decades …

To create a drug, nature's blueprints often have to be improved through semisynthesis or
total synthesis (chemical postevolution). Selected contributions from industrial and academic …

The quinolones trap DNA gyrase and DNA topoisomerase IV on DNA as complexes in
which the DNA is broken but constrained by protein. Early studies suggested that drug …

Over the last decade, methicillin-resistant Staphylococcus aureus (MRSA) strains have
emerged as serious pathogens. These strains are often multiresistant to several antibiotic …

The mutant selection window hypothesis postulates that, for each antimicrobial-pathogen
combination, an antimicrobial concentration range exists in which selective amplification of …

The biodeterioration of artistic and architectural heritage represents a serious and recurring
problem for museums, local authorities, and private collectors alike, where irreparable …

The utility of nitric oxide (NO)-releasing silica nanoparticles as novel antibacterial agents is
demonstrated against Pseudomonas aeruginosa. Nitric oxide-releasing nanoparticles were …