Tyrosine-type site-specific recombinases (T-SSRs) have opened new avenues for the
predictable modification of genomes as they enable precise genome editing in heterologous …

The fields of molecular genetics, biotechnology and synthetic biology are demanding ever
more sophisticated molecular tools for programmed precise modification of cell genomic …

To spread, transposons must integrate into target sites without disruption of essential genes
while avoiding host defense systems. Tn7-like transposons employ multiple mechanisms for …

Prophages control their lifestyle to either be maintained within the host genome or enter the
lytic cycle. Bacillus subtilis contains the SPβ prophage whose lysogenic state depends on …

Mobile genetic elements (MGEs) sequester and mobilize antibiotic resistance genes across
bacterial genomes. Efficient and reliable identification of such elements is necessary to …

Some Bacillus-infecting bacteriophages use a peptide-based communication system,
termed arbitrium, to coordinate the lysis-lysogeny decision. In this system, the phage …

The centromere is the genetic locus that specifies the site of kinetochore assembly, where
the chromosome will attach to the kinetochore microtubule. The pericentromere is the …

Conjugative transposition drives the emergence of multidrug resistance in diverse bacterial
pathogens, yet the mechanisms are poorly characterized. The Tn1549 conjugative …

Bracoviruses (BVs) are endogenized nudiviruses in parasitoid wasps of the microgastroid
complex (order Hymenoptera: Family Braconidae). BVs produce replication-defective virions …

Temperate phage genomes are highly variable mosaic collections of genes that infect a
bacterial host, integrate into the host's genome or replicate as low copy number plasmids …