Members of the protein tyrosine phosphatase (Ptp) family dephosphorylate target proteins
and counter the activities of protein tyrosine kinases that are involved in cellular …

Aberrant protein phosphorylation is one of the hallmarks of cancer cells, and in many cases
a prerequisite to sustain tumor development and progression. Like protein kinases, protein …

Protein tyrosine phosphatases (PTPs) superfamily catalyzes tyrosine de‐phosphorylation
which affects a myriad of cellular processes. Imbalance in signal pathways mediated by …

The R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs) comprises PTPRZ
and PTPRG. A recent study on primary human glioblastomas suggested a close association …

We used an RNAi-mediated loss-of-function screen to study systematically the role of the
protein tyrosine phosphatase (PTP) superfamily of enzymes in mammary epithelial cell …

Protein tyrosine phosphatase receptor gamma (PTPRG) is known to interact with and
regulate several tyrosine kinases, exerting a tumor suppressor role in several type of …

Protein tyrosine phosphorylation is critical for proper function of cells and organisms.
Phosphorylation is regulated by the concerted but generically opposing activities of tyrosine …

Members of the Protein Tyrosine Phosphatase (PTPs) family are associated with growth
regulation and cancer development. Acting as natural counterpart of tyrosine kinases (TKs) …

Chronic myelogenous leukemia (CML) is the most common myeloproliferative disease.
Protein tyrosine phosphatase receptor type γ (PTPRG) is a tumor suppressor gene and a …

Functional studies to identify the potential role of a chromosome 3p14-21 gene, protein
tyrosine phosphatase receptor type G (PTPRG), were performed. PTPRG was identified as a …