Integrins are vital surface adhesion receptors that mediate interactions between the
extracellular matrix (ECM) and cells and are essential for cell migration and the …

Radiotherapy, a treatment method employing radiation to eradicate tumor cells and
subsequently reduce or eliminate tumor masses, is widely applied in the management of …

Protease activated receptors (PARs) are cleaved by coagulation proteases and thereby
connect hemostasis with innate immune responses. Signaling of the tissue factor (TF) …

Simple Summary Neutrophil extracellular traps (NETs) contribute to tumor progression at
different stages, such as primary growth, metastasis, angiogenesis, and cancer-associated …

Pancreatic cancer is characterized by severe metabolic stress due to its prominent
desmoplasia and poor vascularization. Integrin subunit alpha 3 (ITGA3) is a cell surface …

Introduction Microvesicles (MV) released by endothelial cells (EC) following injury or
inflammation contain tissue factor (TF) and mediate communication with the underlying …

Patients with malignant tumors are prone to present hypercoagulability of blood and form
thrombosis, and its pathogenesis is complex involving various factors from clinical and …

Background Tumor recurrence and metastatic progression remains the leading cause for
breast cancer related mortalities. However, the proteomes of patient-matched primary breast …

Abstract The University of North Carolina Symposia on Hemostasis began in 2002, with “The
First Symposium on Hemostasis with a Special Focus on FVIIa and Tissue Factor.” They …

The body's homeostasis depends on the vascular endothelium, which controls
angiogenesis, vascular tone, inflammation, cell trafficking, hemostasis, and the movement of …