Biliary atresia: the animal models

C Petersen - Seminars in pediatric surgery, 2012 - Elsevier
Biliary atresia (BA) is a progressive fibrosing process of the neonatal biliary tree and liver, of
unknown origin, and an as-yet unexplained pathologic mechanism. The crucial point is to …

The sea lamprey as an etiological model for biliary atresia

YW Chung-Davidson, CY Yeh… - BioMed research …, 2015 - Wiley Online Library
Biliary atresia (BA) is a progressive, inflammatory, and fibrosclerosing cholangiopathy in
infants that results in obstruction of both extrahepatic and intrahepatic bile ducts. It is the …

Impact of pre-transplant liver hemodynamics and portal reconstruction techniques on post-transplant portal vein complications in pediatric liver transplantation: a …

C De Magnee, C Bourdeaux, F De Dobbeleer… - Annals of …, 2011 - journals.lww.com
Methods: Three hundred seventy-three children had a primary LT. A detailed ultrasound
study of the pre-LT native liver hemodynamics was available in 198 cases, with details of PV …

Kupffer cells: Important participant of hepatic alveolar echinococcosis

Y Liu, F Tian, J Shan, J Gao, B Li, J Lv… - Frontiers in cellular …, 2020 - frontiersin.org
Aims: Kupffer cells (KCs) are the liver-resident macrophages and play a leading role in the
regulation of liver homeostasis in physiological conditions and in pathology. The study aims …

The interaction of Schistosoma mansoni infection with diabetes mellitus and obesity in mice

AS Amer, AA Othman, LM Dawood, KA El-Nouby… - Scientific Reports, 2023 - nature.com
Human schistosomiasis is one of the most prevalent parasitic diseases worldwide. Various
host factors can affect the host–parasite interactions. Therefore, the aim of the present work …

Effects of selective bile duct ligation on liver parenchyma in young animals: histologic and molecular evaluations

ACA Tannuri, MCM Coelho… - Journal of Pediatric …, 2012 - Elsevier
BACKGROUND/PURPOSE: The mechanisms of increased collagen production and liver
parenchyma fibrosis are poorly understood. These phenomena are observed mainly in …

Antifibrotic effect of AT‐1 blocker and statin in rats with hepatic fibrosis

NE El‐Ashmawy, HA El‐Bahrawy… - Clinical and …, 2015 - Wiley Online Library
Hepatic fibrosis is an outcome of chronic liver injury. Angiotensin II (ANG II) may play a role
in the pathogenesis of hepatic fibrosis. Certain drugs such as ACE inhibitors, ANG II …

Hepatic fibrosis in children and adults

RG Wells - Clinical Liver Disease, 2017 - journals.lww.com
Liver fibrosis is the accumulation of excess matrix—scar tissue—in the liver as part of a
wound-healing response. Although this new matrix is predominantly fibrillar collagen, there …

[HTML][HTML] Dynamic expression of desmin, α-SMA and TGF-β1 during hepatic fibrogenesis induced by selective bile duct ligation in young rats

JO Gonçalves, ACA Tannuri, MCM Coelho… - Brazilian Journal of …, 2014 - SciELO Brasil
We previously described a selective bile duct ligation model to elucidate the process of
hepatic fibrogenesis in children with biliary atresia or intrahepatic biliary stenosis. Using this …

Congenital exposure to Schistosoma mansoni infection: impact on the future immune response and the disease outcome

AA Othman, ZS Shoheib, EM Saied, RH Soliman - Immunobiology, 2010 - Elsevier
Schistosomiasis mansoni is a widespread parasitic infection that may lead to several serious
complications, such as hepatic periportal fibrosis and portal hypertension, mainly due to …