This review deals with emerging evidence of an association between systemic or local
hypoxia and inflammation in a variety of diseases. The evidence points to new ways of …

Delayed graft function is a form of acute renal failure resulting in post-transplantation
oliguria, increased allograft immunogenicity and risk of acute rejection episodes, and …

Ischemia–reperfusion–induced lung injury is characterized by nonspecific alveolar damage,
lung edema, and hypoxemia occurring within 72 hours after lung transplantation. The most …

Lung ischemia-reperfusion injury remains one of the major complications after cardiac
bypass surgery and lung transplantation. Due to its dual blood supply system and the …

The chemokine system coordinates leukocyte migration in immunity and inflammation and is
implicated in the pathogenesis of many human diseases. Although several successful …

Fifteen years have passed since the first description of interleukin (IL)-8/CXCL8 as a potent
neutrophil chemotactic factor. Accumulating evidence has demonstrated that various types …

The neuronal guidance molecule netrin-1 is linked to the coordination of inflammatory
responses. Given that mucosal surfaces are particularly prone to hypoxia-elicited …

Rationale: Primary graft dysfunction is a common complication after lung transplantation and
a significant risk factor for short-and long-term mortality. Objective: We examined the impact …

Rationale: Primary graft dysfunction is a severe acute lung injury syndrome after lung
transplantation. Long-term outcomes of subjects with primary graft dysfunction have not …

Patients awaiting lung transplantation face high wait-list mortality, as injury precludes the
use of most donor lungs. Although ex vivo lung perfusion (EVLP) is able to recover marginal …