Tremendous progress has been made in the field of toxicology leading to the advance of
developmental toxicity assessment. Conventional animal models and in vitro two …

Abstract Three-dimensional (3D) bioprinting is an emerging technology that is widely used
in regenerative medicine. With the continuous development of the technology, it has …

Background Recently, great efforts have been made to design protocols for obtaining ocular
cells from human stem cells to model diseases or for regenerative purposes. Current …

Replenishing the retina with retinal pigment epithelial (RPE) cells derived from pluripotent
stem cells (PSCs) has great promise for treating retinal degenerative diseases, but it is …

Organ transplantation is understood as a technique where an organ from a donor patient is
transferred to a recipient patient. This practice gained strength in the 20th century and …

Recent breakthroughs in developing human-relevant organotypic models led to the building
of highly resemblant tissue constructs that hold immense potential for transplantation, drug …

Background: The aim of this study was to test the feasibility and safety of subretinal
transplantation of human induced pluripotent stem cell (hiPSC)-derived retinal pigment …

Human pluripotent stem cell (hPSC)-derived retinal organoids are three-dimensional
cellular aggregates that differentiate and self-organize to closely mimic the spatial and …

Nerve decellularized matrix (NDM) has received much attention due to its natural
composition and structural advantages that had proven to be an excellent candidate for …

Reliable prediction of compound mediated nephrotoxicity in humans is still unsatisfactory
irrespective of the recent advancements in in silico, in vitro and in vivo models. Therefore …