Exploring the partial degradation of polysaccharides: Structure, mechanism, bioactivities, and perspectives

SK Chen, X Wang, YQ Guo, XX Song… - … Reviews in Food …, 2023 - Wiley Online Library
Polysaccharides are promising biomolecules with lowtoxicity and diverse bioactivities in
food processing and clinical drug development. However, an essential prerequisite for their …

Acidic natural deep eutectic solvents as dual solvents and catalysts for the solubilization and deglycosylation of soybean isoflavone extracts: Genistin as a model …

J Chen, Y Ni, P Zhang, X Liang, S Fang - Food Chemistry, 2023 - Elsevier
This study investigated the possibility of using green solvent natural deep eutectic solvents
(NADESs) as dual solvent-catalysts for the solubilization and deglycosylation of soybean …

New insights of flavonoid glycosidases and their application in food industry

Y Liu, Q Yang, Y Guo, Y Jiang, H Zhu… - Critical Reviews in Food …, 2023 - Taylor & Francis
Flavonoids are significant natural nutraceuticals and a key component of dietary
supplements. Given that flavonoid glycosides are more plentiful in nature and less beneficial …

Fundamental insight into glycoside hydrolase-catalyzed hydrolysis of the universal Koshland substrates–glycopyranosyl fluorides

M Farren-Dai, N Sannikova, K Swiderek, V Moliner… - ACS …, 2021 - ACS Publications
We measured a panel of five kinetic isotope effects [KIEs; three secondary deuterium (1-, 2-,
and 5-2H) and two primary (1-13C and 5-18O) effects] for the catalyzed hydrolysis of α-d …

Allylic Carbocyclic Inhibitors Covalently Bind Glycoside Hydrolases

TD Grayfer, K Yamani, E Jung, GA Chesnokov… - JACS Au, 2023 - ACS Publications
Allylic cyclitols were investigated as covalent inhibitors of glycoside hydrolases by chemical,
enzymatic, proteomic, and computational methods. This approach was inspired by the C7 …

Replacement of oxocarbenium ions by allylic cations in both enzymatic and spontaneous reactions of glycosides

PM Danby - 2021 - open.library.ubc.ca
Oxocarbenium ions play a pivotal role in the chemistry and biochemistry of glycosides. In
this thesis I prepared carbocyclic glycoside analogs that can generate allylic cations in the …