Inhibition of N-linked glycosylation by tunicamycin may contribute to the treatment of SARS-CoV-2

AA Dawood, MA Altobje - Microbial pathogenesis, 2020 - Elsevier
SARS-CoV-2 remains a medical and economic challenge, due to the lack of a suitable drug
or vaccine. The glycans in some proteins play a pivotal role in protein folding …

[PDF][PDF] Molecular docking of SARS-CoV-2 nucleocapsid protein with angiotensin-converting enzyme II

A Dawood, M Altobje, Z Alrassam - Mikrobio Zhu, 2021 - researchgate.net
SARS-CoV-2 remains life-threatening human pathogen witnessed in the present world.
Purpose. The key objective of this research was to incorporate a bioinformatics technique to …

Glycosylation, ligand binding sites and antigenic variations between membrane glycoprotein of COVID-19 and related coronaviruses

AA Dawood - Vacunas, 2021 - Elsevier
A new coronavirus strain has wreaked havoc on human lives so the WHO was declared as a
pandemic since 20th March 2020. The Membrane glycoprotein MP spans the viral envelope …

[PDF][PDF] Identification of cytotoxic t-cell and b-cell epitopes in the nucleocapsid phosphoprotein of sars-cov-2 using immunoinformatics

AA Dawood - Mikrobiol. Zh, 2021 - researchgate.net
Last December, a novel coronavirus emerged in Wuhan city, China. Severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2) causes a high intense acute respiratory …

Determination of binding affinity of tunicamycin with SARS-CoV-2 proteins: Proteinase, protease, nsp2, nsp9, ORF3a, ORF7a, ORF8, ORF9b, envelope and RBD of …

AA Dawood - Vacunas, 2023 - Elsevier
Introduction Despite the availability of several COVID-19 vaccines, the incidence of
infections remains a serious issue. Tunicamycin (TM), an antibiotic, inhibited tumor growth …