Vincristine-induced peripheral neurotoxicity (VIPN) is a very common side effect of
vincristine chemotherapy among pediatric patients with cancer. Neuropathy may be sensory …

Purpose Vincristine is widely used as anticancer therapy for a variety of hematological
malignancies. The treatment is limited by progressive vincristine-induced neuropathy …

Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating
condition associated with a number of chemotherapeutic agents. Drugs commonly …

During the last few decades, pediatric acute lymphoblastic leukemia (ALL) cure rates have
improved significantly with rates exceeding 90%. Parallel to this remarkable improvement …

The integration of genomic data into personalized treatment planning has revolutionized
oncology care. Despite this, patients with cancer remain vulnerable to high rates of adverse …

Vincristine (VCR) is the first-line chemotherapeutic medication often co-administered with
other drugs to treat childhood acute lymphoblastic leukemia. Dose-dependent neurotoxicity …

Despite significant advances in cancer therapeutics, chemotherapy remains the cornerstone
of treatment for many tumors. Importantly, however, chemotherapy-induced toxicity …

Objectives This systematic review provides an overview of the effect of undernutrition on the
pharmacokinetics of chemotherapy in children with cancer. Methods PubMed, Embase, and …

Vincristine (VCR), an effective antitumor drug, has been utilized in several polytherapy
regimens for acute lymphoblastic leukemia, neuroblastoma and rhabdomyosarcoma …

Chemotherapy‐induced peripheral neuropathy (CIPN) is a common dose‐limiting toxicity
that affects 30%–40% of patients undergoing cancer treatment. Although multiple …