Western societies notice an increasing interest in plant-based eating patterns such as
vegetarian and vegan, yet potential effects on the body and brain are a matter of debate …

Sirtuins are the class III of histone deacetylases whose deacetylate of histones is dependent
on nicotinamide adenine dinucleotide (NAD+). Among seven sirtuins, SIRT1 plays a critical …

Dietary polyphenols have been the focus of major interest for their potential benefits on
human health. Several preclinical studies have been conducted to provide a rationale for …

Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

Resveratrol is a bioactive compound in many foods. Since its anticancer activity was
reported in 1997, its health benefits have been intensively investigated. Resveratrol has …

Cellular oxidation–reduction (redox) systems, which encompass pro‐and antioxidant
molecules, are integral components of a plethora of essential cellular processes. Any …

Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders,
and neurodegenerative disease. There is emerging evidence that interventions that improve …

Neurodegenerative diseases are characterized by the progressive loss of neurons in
different regions of the nervous system. Alzheimer's disease (AD) and Parkinson's disease …

So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …

The human sirtuins are a group of NAD+-dependent protein deacylases. They “erase” acyl
modifications from lysine residues in various cellular targets including histones, transcription …