Application of chemometrics using direct spectroscopic methods as a QC tool in pharmaceutical industry and their validation

L Wulandari, R Idroes, TR Noviandy… - Profiles of Drug …, 2022 - Elsevier
This present review described the application of chemometrics using direct spectroscopic
methods at the quality control (QC) laboratory of Pharmaceutical Industries. Using …

Matrix systems for oral drug delivery: Formulations and drug release

G Vasvári, J Kalmár, P Veres, M Vecsernyés… - Drug Discovery Today …, 2018 - Elsevier
In this current article matrix formulations for oral drug delivery are reviewed. Conventional
dosage forms and novel applications such as 3D printed matrices and aerogel matrices are …

[图书][B] Profiles of drug substances, excipients, and related methodology

A Al-Majed - 2022 - books.google.com
Profiles of Drug Substances, Excipients, and Related Methodology, Volume 47 covers all
aspects of drug development and formulation of drugs, meeting the information needs of the …

Wavelength feature mapping as a proxy to mineral chemistry for investigating geologic systems: An example from the Rodalquilar epithermal system

F van der Meer, V Kopačková, L Koucká… - International journal of …, 2018 - Elsevier
The final product of a geologic remote sensing data analysis using multi spectral and
hyperspectral images is a mineral (abundance) map. Multispectral data, such as ASTER …

Determination of starch crystallinity with the Fourier-transform terahertz spectrometer

S Nakajima, S Horiuchi, A Ikehata, Y Ogawa - Carbohydrate Polymers, 2021 - Elsevier
We measured the terahertz (THz) spectra of native, amorphous, and dried starches derived
from corn and potato using the Fourier-transform (FT) system and compared these spectra to …

[HTML][HTML] Quantitative analysis and evaluation of solid-state stability of mebendazole Forms A and C suspensions by powder X-ray diffraction using the Rietveld method

JT Chambi, LD Prado, BF de Carvalho Patricio… - International Journal of …, 2024 - Elsevier
Mebendazole (MBZ) is a broad-spectrum active pharmaceutical ingredient (API) indicated
for treating parasitosis, and it has three solid-state forms, A, B, and C. These solid forms …

Portable near-infrared instruments: Application for quality control of polymorphs in pharmaceutical raw materials and calibration transfer

VH da Silva, JJ da Silva, CF Pereira - Journal of pharmaceutical and …, 2017 - Elsevier
This work presents an evaluation of the analytical performance of three different portable
near-infrared (NIR) instruments (denominated Port. 1, Port. 2 and Port. 3) for quantifying …

Chemometrics-assisted solid-state characterization of pharmaceutically relevant materials. Polymorphic substances

NL Calvo, RM Maggio, TS Kaufman - Journal of pharmaceutical and …, 2018 - Elsevier
Current regulations command to properly characterize pharmaceutically relevant solid
systems. Chemometrics comprise a range of valuable tools, suitable to process large …

Mebendazole crystal forms in tablet formulations. An ATR-FTIR/chemometrics approach to polymorph assignment

NL Calvo, TS Kaufman, RM Maggio - Journal of Pharmaceutical and …, 2016 - Elsevier
Structural polymorphism of active pharmaceutical ingredients (API) is a relevant concern for
the modern pharmaceutical industry, since different polymorphic forms may display …

Multivariate quantification of mebendazole polymorphs by terahertz time domain spectroscopy (THZ-TDS)

VH Da Silva, FS Vieira, JJR Rohwedder, C Pasquini… - Analyst, 2017 - pubs.rsc.org
This work presents an analytical method based on terahertz-time domain spectroscopy (THz-
TDS) and partial least squares (PLS) regression models to quantify mebendazole (MBZ) …