Renal fibrosis, particularly tubulointerstitial fibrosis, is the common final outcome of almost
all progressive chronic kidney diseases. Renal fibrosis is also a reliable predictor of …

Renal fibrosis is the usual outcome of an excessive accumulation of extracellular matrix
(ECM) that frequently occurs in membranous and diabetic nephropathy. The result of renal …

Kidney disease associated with diabetes mellitus is a major health problem worldwide.
Although established therapeutic strategies, such as appropriate blood glucose control …

Autosomal dominant polycystic kidney disease (ADPKD) is a progressive inherited disorder
in which renal tissue is gradually replaced with fluid-filled cysts, giving rise to chronic kidney …

MicroRNAs (miRNAs) are a class of small noncoding RNAs that regulate gene expression
by targeting mRNAs to trigger either translation repression or mRNA degradation. miR-125b …

Acute kidney injury (AKI) is one of the main conditions responsible for chronic kidney
disease (CKD), including end-stage renal disease (ESRD) as a long-term complication …

Polycystic kidney disease (PKD) is a commonly inherited disorder characterized by cyst
formation and fibrosis (Wilson, N Engl J Med 350: 151–164, 2004) and is caused by …

The age on onset of decline in renal function and end-stage renal disease (ESRD) in
autosomal polycystic kidney disease (ADPKD) is highly variable and there are currently no …

In autosomal dominant polycystic kidney disease (ADPKD), the inexorable growth of
numerous fluid-filled cysts leads to massively enlarged kidneys, renal interstitial damage …

The central goal of this overview article is to summarize recent findings in renal epithelial
transport, focusing chiefly on the connecting tubule (CNT) and the cortical collecting duct …