ANPELA: Significantly Enhanced Quantification Tool for Cytometry‐Based Single‐Cell Proteomics
Y Zhang, H Sun, X Lian, J Tang, F Zhu - Advanced science, 2023 - Wiley Online Library
ANPELA is widely used for quantifying traditional bulk proteomic data. Recently, there is a
clear shift from bulk proteomics to the single‐cell ones (SCP), for which powerful cytometry …
clear shift from bulk proteomics to the single‐cell ones (SCP), for which powerful cytometry …
Assessing the potential contribution of in silico studies in discovering drug candidates that interact with various SARS-CoV-2 receptors
AGA Mushebenge, SC Ugbaja, NA Mbatha… - International Journal of …, 2023 - mdpi.com
The COVID-19 pandemic has spurred intense research efforts to identify effective treatments
for SARS-CoV-2. In silico studies have emerged as a powerful tool in the drug discovery …
for SARS-CoV-2. In silico studies have emerged as a powerful tool in the drug discovery …
[HTML][HTML] In-vitro and computational analysis of Urolithin-A for anti-inflammatory activity on Cyclooxygenase 2 (COX-2)
AG Revankar, ZK Bagewadi, IA Shaikh… - Saudi Journal of …, 2023 - Elsevier
Abstract Cyclooxygenase 2 (COX-2) participates in the inflammation process by converting
arachidonic acid into prostaglandin G2 which increases inflammation, pain and fever. COX …
arachidonic acid into prostaglandin G2 which increases inflammation, pain and fever. COX …
Exploration of phytochemical compounds against Marburg virus using QSAR, molecular dynamics, and free energy landscape
AA Rabaan, MA Halwani, M Garout, J Alotaibi… - Molecular Diversity, 2023 - Springer
Marburg virus disease (MVD) is caused by the Marburg virus, a one-of-a-kind zoonotic RNA
virus from the genus Filovirus. Thus, this current study employed AI-based QSAR and …
virus from the genus Filovirus. Thus, this current study employed AI-based QSAR and …
Pharmacoinformatics approach for the screening of Kovidra (Bauhinia variegata) phytoconstituents against tumor suppressor protein in triple negative breast cancer
P More-Adate, KB Lokhande… - Journal of …, 2024 - Taylor & Francis
Abstract Globally, 2.3 million women were diagnosed with breast cancer, with 6, 85000
mortalities in year 2021; making it the world's most prevalent cancer. This growing global …
mortalities in year 2021; making it the world's most prevalent cancer. This growing global …
An in-silico investigation and network pharmacology based approach to explore the anti-breast-cancer potential of Tecteria coadunata (Wall.) C. Chr.
Uncontrolled cell proliferation is a common definition of cancer. After lung carcinoma, breast
neoplasm is the second-most prevalent kind of cancer. The majority of breast cancer cells …
neoplasm is the second-most prevalent kind of cancer. The majority of breast cancer cells …
The novel anti-cancer feature of Brazzein through activating of hTLR5 by integration of biological evaluation: molecular docking and molecular dynamics simulation
M Poursalim, MD Shasaltaneh, V Jafarian… - Scientific Reports, 2022 - nature.com
Many of plant proteins exhibit the properties similar to the antitumor proteins although the
anticancer activity of Brazzein on modulating the autophagy signaling pathway has not been …
anticancer activity of Brazzein on modulating the autophagy signaling pathway has not been …
[HTML][HTML] Development of newer generation Vascular endothelial growth factor Receptor-2 Inhibitors: Pharmacophore based design, virtual Screening, molecular …
Abstract Vascular Endothelial Growth Factor (VEGF) has a greater impact on
carcinogenesis, and it is the most significant receptor in mediating the mutagenesis and …
carcinogenesis, and it is the most significant receptor in mediating the mutagenesis and …
Design of novel isoxazole derivatives as tubulin inhibitors using computer-aided techniques: QSAR modeling, in silico ADMETox, molecular docking, molecular …
In the current work, computational methods were used to investigate new isoxazole
derivatives that could be used as tubulin inhibitors. The study aims to develop a reliable …
derivatives that could be used as tubulin inhibitors. The study aims to develop a reliable …
Unraveling the therapeutic potential of Senna singueana phytochemicals to attenuate pancreatic cancer using protein–protein interactions, molecular docking, and …
Pancreatic cancer (PC) presents challenges due to limited treatment options and patients
seek complementary therapies alongside conventional treatments to improve well-being …
seek complementary therapies alongside conventional treatments to improve well-being …