Natural products and their structural analogues have historically made a major contribution
to pharmacotherapy, especially for cancer and infectious diseases. Nevertheless, natural …

Rare actinomycetes are prolific in the marine environment; however, knowledge about their
diversity, distribution and biochemistry is limited. Marine rare actinomycetes represent a …

The vast majority of systemic bacterial infections are caused by facultative, often antibiotic-
resistant, pathogens colonizing human body surfaces. Nasal carriage of Staphylococcus …

Microbial natural products are a tremendous source of new bioactive chemical entities for
drug discovery. Next generation sequencing has revealed an unprecedented genomic …

Actinomycetes have been proven to be an excellent source of secondary metabolites for
more than half a century. Exhibiting various bioactivities, they provide valuable approved …

The problem of antibiotic resistance has become a challenge for our public health and
society; it has allowed infectious diseases to re-emerge as a risk to human health. New …

Xenorhabdus and Photorhabdus species dedicate a large amount of resources to the
production of specialized metabolites derived from non-ribosomal peptide synthetase …

Insects and fungal pathogens pose constant problems to public health and agriculture,
especially in resource-limited parts of the world; and the use of chemical pesticides …

Plant endophytes are microorganisms that live in healthy plant tissues in part or all of their
life history without causing obvious symptoms of infection in the host plants. Endophytes, a …

Covering: up to November 2017 Organismic interaction is one of the fundamental principles
for survival in any ecosystem. Today, numerous examples show the interaction between …