Recent research has highlighted the importance of key tumor microenvironment features,
notably the collagen-rich extracellular matrix (ECM) in characterizing tumor invasion and …

It has become clear that carcinogenesis goes beyond tumor cell biology. Cancer research
has acknowledged the importance of biological functions of the tumor-microenvironment …

Contact guidance is a powerful topographical cue that induces persistent directional cell
migration. Healthy tissue stroma is characterized by a meshwork of wavy extracellular matrix …

Remodeling of the extracellular matrix (ECM) is an important part in the development and
progression of many epithelial cancers. However, the biological significance of collagen …

This chapter highlights methods for visualization and analysis of extracellular matrix (ECM)
proteins, with particular emphasis on collagen type I, the most abundant protein in …

Despite careful staging, the accuracy for preoperative detection of small distant metastases
remains poor, creating a clinical need for enhanced operative staging to detect occult …

Optical waveguiding phenomena found in bioinspired chemically synthesized peptide
nanostructures are a new paradigm which can revolutionize emerging fields of precise …

Ovarian cancer remains the deadliest of the gynecological cancers, where this arises from
poor screening and imaging tools that can detect early disease, and also limited …

Nonlinear disordered photonic media (NDPM), composed of a random configuration of
noncentrosymmetric crystals, offer a versatile platform to tailor nonlinear optical effects. The …

Simple Summary The collagen architecture in the extracellular matrix (ECM) is highly
remodeled in high grade serous ovarian cancer (HGSOC). Many of these tumors begin in …