The first edition of the European LeukemiaNet (ELN) recommendations for diagnosis and
management of acute myeloid leukemia (AML) in adults, published in 2010, has found …

The genetic landscape of classical myeloproliferative neoplasm (MPN) is in large part
elucidated. The MPN-restricted driver mutations, including those in JAK2, calreticulin …

Although much work has focused on the elucidation of somatic alterations that drive the
development of acute leukaemias and other haematopoietic diseases, it has become …

Abstract BCR:: ABL1-negative myeloproliferative neoplasms (MPNs) are clonal diseases
originating from a single hematopoietic stem cell that cause excessive production of mature …

Philadelphia-negative classical myeloproliferative neoplasms (MPNs) include polycythemia
vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). The 2016 …

Substantial progress has been made in our understanding of the pathogenetic basis of
myeloproliferative neoplasms. The discovery of mutations in JAK2 over a decade ago …

Recently, DDX41 mutations have been identified both as germline and acquired somatic
mutations in families with multiple cases of late-onset myelodysplastic syndrome (MDS) …

Knowledge on the myeloproliferative neoplasms (MPNs)–polycythemia vera (PV), essential
thrombocythemia (ET), primary myelofibrosis (PMF)–has accumulated since the discovery of …

Myeloproliferative neoplasms (MPNs) are a group of related clonal hematologic disorders
characterized by excess accumulation of one or more myeloid cell lineages and a tendency …

As germline predisposition to hematopoietic malignancies has gained increased recognition
and attention in the field of oncology, it is important for clinicians to use a systematic …