HIV and antiretroviral therapy-related fat alterations

JR Koethe, C Lagathu, JE Lake, P Domingo… - Nature reviews Disease …, 2020 - nature.com
Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …

Systematic review: the epidemiology and natural history of non‐alcoholic fatty liver disease and non‐alcoholic steatohepatitis in adults

G Vernon, A Baranova… - Alimentary pharmacology …, 2011 - Wiley Online Library
Aliment Pharmacol Ther 2011; 34: 274–285 Summary Background Non‐alcoholic fatty liver
disease (NAFLD) is a common cause of chronic liver disease, and its worldwide prevalence …

Extensive summary of the important roles of indole propionic acid, a gut microbial metabolite in host health and disease

H Jiang, C Chen, J Gao - Nutrients, 2022 - mdpi.com
Increasing evidence suggests that metabolites produced by the gut microbiota play a crucial
role in host–microbe interactions. Dietary tryptophan ingested by the host enters the gut …

Prevalence and risk factors of nonalcoholic fatty liver disease in HIV-monoinfection

JB Maurice, A Patel, AJ Scott, K Patel, M Thursz… - Aids, 2017 - journals.lww.com
Objective: To identify the prevalence and risk factors of nonalcoholic fatty liver disease
(NAFLD), nonalcoholic steatohepatitis (NASH) and fibrosis in HIV-monoinfected patients …

Obesity and weight gain in persons with HIV

SS Bailin, CL Gabriel, CN Wanjalla… - Current HIV/AIDS Reports, 2020 - Springer
Abstract Purpose of Review The proportion of overweight and obese persons with HIV
(PWH) has increased since the introduction of antiretroviral therapy (ART). We aim to …

Stratifying the risk of NAFLD in patients with HIV under combination antiretroviral therapy (cART)

J Bischoff, W Gu, C Schwarze-Zander… - …, 2021 - thelancet.com
Background De novo steatosis is the main criteria for non-alcoholic fatty liver disease
(NAFLD), which is becoming a clinically relevant comorbidity in HIV-infected patients. This …

Metabolic complications affecting adipose tissue, lipid and glucose metabolism associated with HIV antiretroviral treatment

C Lagathu, V Béréziat, J Gorwood… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Efficient antiretroviral-treatment (ART) generally allows control of HIV infection.
However, persons-living-with-HIV (PLWH), when aging, present a high prevalence of …

Increasing burden of liver disease in patients with HIV infection

D Joshi, J O'Grady, D Dieterich, B Gazzard, K Agarwal - The Lancet, 2011 - thelancet.com
Introduction of effective combined antiretroviral therapy has made HIV infection a chronic
illness. Substantial reductions in the number of AIDS-related deaths have been …

Prevalence and characteristics of nonalcoholic fatty liver disease and fibrosis in people living with HIV monoinfection: a systematic review and meta-analysis

M Kalligeros, A Vassilopoulos, F Shehadeh… - Clinical …, 2023 - Elsevier
Background and Aims Liver disease remains a leading cause of morbidity and mortality
among people living with HIV (PLWH). Emerging data suggest that PLWH are at high risk for …

[HTML][HTML] Role of nonalcoholic fatty liver disease as risk factor for drug-induced hepatotoxicity

J Massart, K Begriche, C Moreau… - Journal of clinical and …, 2017 - ncbi.nlm.nih.gov
Background: Obesity is often associated with nonalcoholic fatty liver disease (NAFLD),
which refers to a large spectrum of hepatic lesions including fatty liver, nonalcoholic …