Lipid droplets (LDs) are intracellular organelles that store neutral lipids within cells. Over the
last two decades there has been a dramatic growth in our understanding of LD biology and …

Dyslipidemia, characterized by increased plasma levels of low-density lipoprotein
cholesterol (LDL-C), very low-density lipoprotein cholesterol (VLDL-C), triglyceride (TG), and …

Over the past decade, interest in caveolae biology has peaked. These small bulb-shaped
plasma membrane invaginations of 50–80 nm diameter present in most cell types have …

The specific role of dietary fat in breast cancer progression is unclear, although a low-fat diet
was associated with decreased recurrence of estrogen receptor alpha negative (ER−) breast …

The expansion of adipose tissue is an adaptive mechanism that increases nutrient buffering
capacity in response to an overall positive energy balance. Over the course of expansion …

In the general context of an increasing prevalence of obesity-associated diseases, which
follows changing paradigms in food consumption and worldwide use of industry-transformed …

The role of protein kinase C (PKCs) isoforms in the regulation of glucose metabolism by
insulin is complex, partly due to the large PKC family consisting of three sub-groups …

OBJECTIVE Ceramide is now recognized as a negative regulator of insulin signaling by
impairing protein kinase B (PKB)/Akt activation. In different cells, two distinct mechanisms …

The ratio of free fatty acid (FFA) turnover decreases significantly with the expansion of white
adipose tissue. Adipose tissue and dietary saturated fatty acid levels significantly correlate …

Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular
lipid droplets but their role in this location remains unclear. By studying primary adipocytes …