Liver disease is a major global health-care problem, affecting an estimated 844 million
people worldwide. Despite this substantial burden, therapeutic options for liver disease …

The lymphatic system (LS) is composed of lymphoid organs and a network of vessels that
transport interstitial fluid, antigens, lipids, cholesterol, immune cells, and other materials in …

Normothermic machine perfusion (NMP) has emerged as an innovative organ preservation
technique. Developing an understanding for the donor organ immune cell composition and …

Endothelial cells throughout the body are heterogeneous, and this is tightly linked to the
specific functions of organs and tissues. Heterogeneity is already determined from …

Lymphatic vessels, comprising the secondary circulatory system in human body, play a
multifaceted role in maintaining homeostasis among various tissues and organs. They are …

Cholestatic liver injuries, characterized by regional damage around the bile ductular region,
lack curative therapies and cause considerable mortality. Here we generated a high …

In recent years, significant advances have been made in the study of lymphatic vessels with
the identification of their specific markers and the development of research tools that have …

Blood vessels have long been considered as passive conduits for delivering blood.
However, in recent years, cells of the vessel wall (endothelial cells, smooth muscle cells and …

In recent years, the study of lymphangiogenesis and fibrotic diseases has made
considerable achievements, and accumulating evidence indicates that lymphangiogenesis …

Myocardial fibrosis is a key pathologic feature of hypertrophic cardiomyopathy (HCM).
However, the fibrotic pathways activated by HCM-causing sarcomere protein gene …