Triazole hybrid compounds: A new frontier in malaria treatment

L Ravindar, SA Hasbullah, KP Rakesh… - European Journal of …, 2023 - Elsevier
Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …

An updated review on diverse range of biological activities of 1, 2, 4-triazole derivatives: Insight into structure activity relationship

O Gupta, T Pradhan, G Chawla - Journal of Molecular Structure, 2023 - Elsevier
Abstract Since its discovery 1, 2, 4-triazole ring has emerged as a prominent heterocyclic
scaffold in medicinal chemistry. It possesses a wide spectrum of biological activities such as …

[HTML][HTML] The fate of heterogeneous catalysis & click chemistry for 1, 2, 3-triazoles: Nobel prize in chemistry 2022

V Kumar, K Lal, RK Tittal - Catalysis Communications, 2023 - Elsevier
The demand for environmental friendly methodologies had shifted the the approach of
scientific community for using easy and green reaction conditions instead of using …

Emerging impact of triazoles as anti-tubercular agent

A Sharma, AK Agrahari, S Rajkhowa… - European Journal of …, 2022 - Elsevier
Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …

Synthesis, antimicrobial, antibiofilm and computational studies of isatin-semicarbazone tethered 1, 2, 3-triazoles

A Kumar, K Lal, V Kumar, M Murtaza, S Jaglan… - Bioorganic …, 2023 - Elsevier
In present era, heterocyclic compounds containing two or three nitrogen atoms play a vital
role in drug discovery. In this context, a new class of isatin-semicarbazone tethered 1, 2, 3 …

Rationale design, synthesis, cytotoxicity evaluation, and in silico mechanistic studies of novel 1, 2, 3-triazoles with potential anticancer activity

EM Othman, EA Fayed, EM Husseiny… - New Journal of …, 2022 - pubs.rsc.org
A new set of 1, 2, 3-triazoles was designed and synthesized to evaluate their potential to
inhibit the growth of cancer cells. Thiazole, thiazolone, and hydrazine as effective fragments …

A mini review on pharmacological significance of isatin-1, 2, 3-triazole hybrids

A Kumar, Y Rohila, V Kumar… - Current Topics in Medicinal …, 2023 - ingentaconnect.com
Molecular hybridization is one of the recent stratagems in medicinal chemistry to synthesize
a novel hybrid molecule having better affinity and efficacy by combining two or more …

Synthesis, antimicrobial activity and molecular docking of novel benzimidazole conjugated 1, 2, 3-triazole analogues

V Mallikanti, V Thumma, R Matta, KR Valluru… - Chemical Data …, 2023 - Elsevier
A library of novel benzimidazole based 1, 2, 3-triazoles were synthesized by a series of
reactions containing Suzuki coupling, cyclization and microwave assisted copper catalyzed …

[HTML][HTML] Recent advances in chalcone-triazole hybrids as potential pharmacological agents

A Bhukal, V Kumar, LK Kumar, K Lal - Results in Chemistry, 2023 - Elsevier
Molecular hybridization is one of the recent strategies to synthesize a novel hybrid
compound by combining two or more pharmacophoric units. Being a linkage process, it …

[HTML][HTML] Synthesis, antimicrobial evaluation and docking studies of fluorinated imine linked 1, 2, 3-triazoles

A Kumar, K Lal, N Poonia, A Kumar… - Research on Chemical …, 2022 - Springer
A diverse series of imine linked 1, 2, 3-triazole hybrids has been synthesized via Cu (I)-
promoted click reaction, with an aim to develop some new antimicrobial molecules. The …