Despite early diagnosis and treatment, almost 20% of patients with early-stage (cT1-cT2N0)
oral tongue squamous cell carcinoma (OTSCC) still die of their disease. The prognosis of …

Background Radiotherapy is widely used in contemporary head and neck cancer treatment
protocols. The ability of head and neck radiotherapy (HNRT) to cause direct radiogenic …

Introduction Biologic aggressiveness of OSCC (Oral Cavity Squamous Cell Carcinoma), has
intrigued research in various prognosticating histopathological markers over past few …

Background Tongue cancer is associated with debilitating diseases and poor prognostic
outcomes. The use of imaging techniques like ultrasonography to assist in the clinical …

Aims Oral squamous cell carcinoma (OSCC) is a common malignancy with a variable
clinical course. One of the established survival predictors in carcinomas in general is tumour …

Background The prognostic significance of tumour budding (TB) and minimal cell nest size
(MCNS) was shown in human papillomavirus (HPV)-negative head and neck squamous cell …

Aims Oral tongue squamous cell carcinoma (OTSCC) has a relatively poor outcome, and
there is a need to identify better prognostic factors. Recently, tumour–stroma ratio (TSR) has …

Objective This study evaluated the association of four histopathological grading systems
(WHO grading system, malignancy grading of the deep invasive margins (MG), histological …

Aims Previous studies have demonstrated that the tumour–stroma ratio (TSR) and tumour
budding are of prognostic value for oral squamous cell carcinomas (OSCCs). The aim of this …

Abstract The World Health Organization (WHO) grading system has a low prognostic value
for early-stage oral tongue squamous cell carcinoma; greater prognostic power has been …