Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

Metabolic homeostasis emerges from the complex, multidirectional crosstalk between key
metabolic tissues including adipose tissue, liver, and skeletal muscle. This crosstalk …

Background—Hypoxia induces an inflammatory response in the lung manifested by
alternative activation of macrophages with elevation of proinflammatory mediators that are …

In multicellular organisms, communication between cells mainly involves the secretion of
proteins that then bind to receptors on neighbouring cells. But another mode of intercellular …

Mammalian cells secrete two types of extracellular vesicles either constitutively or in a
regulated manner: exosomes (50–100 nm in diameter) released from the intracellular …

Oligodendrocytes secrete vesicles into the extracellular space, where they might play a role
in neuron–glia communication. These exosomes are small vesicles with a diameter of 50 …

Adipose tissue (AT) is a highly heterogeneous and dynamic organ that plays important roles
in regulating energy metabolism and insulin sensitivity. In addition to its classical roles in …

Exosomes are 40–100-nm diameter membrane vesicles of endocytic origin that are
released by most cell types upon fusion of multivesicular bodies with the plasma membrane …

Exosomes are 40–100 nm membrane vesicles of endocytic origin secreted by most cell
types in vitro. Recent studies have shown that exosomes are also found in vivo in body fluids …

BACKGROUND Genomic studies have yielded important insights into the pathogenesis of
obesity. Circulating microRNAs (miRNAs) are valuable biomarkers of systemic diseases and …