On modeling

DS Novikov, VG Kiselev… - Magnetic resonance in …, 2018 - Wiley Online Library
Mapping tissue microstructure with MRI holds great promise as a noninvasive window into
tissue organization at the cellular level. Having originated within the realm of diffusion NMR …

Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation

DS Novikov, E Fieremans, SN Jespersen… - NMR in …, 2019 - Wiley Online Library
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

[HTML][HTML] Investigating white matter fibre density and morphology using fixel-based analysis

DA Raffelt, JD Tournier, RE Smith, DN Vaughan… - Neuroimage, 2017 - Elsevier
Voxel-based analysis of diffusion MRI data is increasingly popular. However, most white
matter voxels contain contributions from multiple fibre populations (often referred to as …

Imaging brain microstructure with diffusion MRI: practicality and applications

DC Alexander, TB Dyrby, M Nilsson… - NMR in …, 2019 - Wiley Online Library
This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …

Multi-tissue constrained spherical deconvolution for improved analysis of multi-shell diffusion MRI data

B Jeurissen, JD Tournier, T Dhollander, A Connelly… - NeuroImage, 2014 - Elsevier
Constrained spherical deconvolution (CSD) has become one of the most widely used
methods to extract white matter (WM) fibre orientation information from diffusion-weighted …

[HTML][HTML] SANDI: a compartment-based model for non-invasive apparent soma and neurite imaging by diffusion MRI

M Palombo, A Ianus, M Guerreri, D Nunes… - Neuroimage, 2020 - Elsevier
This work introduces a compartment-based model for apparent cell body (namely soma) and
neurite density imaging (SANDI) using non-invasive diffusion-weighted MRI (DW-MRI). The …

NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain

H Zhang, T Schneider, CA Wheeler-Kingshott… - Neuroimage, 2012 - Elsevier
This paper introduces neurite orientation dispersion and density imaging (NODDI), a
practical diffusion MRI technique for estimating the microstructural complexity of dendrites …

[HTML][HTML] Multi-compartment microscopic diffusion imaging

E Kaden, ND Kelm, RP Carson, MD Does… - NeuroImage, 2016 - Elsevier
This paper introduces a multi-compartment model for microscopic diffusion anisotropy
imaging. The aim is to estimate microscopic features specific to the intra-and extra-neurite …

Degeneracy in model parameter estimation for multi‐compartmental diffusion in neuronal tissue

IO Jelescu, J Veraart, E Fieremans… - NMR in …, 2016 - Wiley Online Library
The ultimate promise of diffusion MRI (dMRI) models is specificity to neuronal microstructure,
which may lead to distinct clinical biomarkers using noninvasive imaging. While multi …

A pathophysiological framework of hippocampal dysfunction in ageing and disease

SA Small, SA Schobel, RB Buxton, MP Witter… - Nature Reviews …, 2011 - nature.com
The hippocampal formation has been implicated in a growing number of disorders, from
Alzheimer's disease and cognitive ageing to schizophrenia and depression. How can the …