HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation

MA Checkley, BG Luttge, EO Freed - Journal of molecular biology, 2011 - Elsevier
The HIV-1 envelope (Env) glycoproteins play an essential role in the virus replication cycle
by mediating the fusion between viral and cellular membranes during the entry process. The …

Pathogenesis of human immunodeficiency virus infection

JA Levy - Microbiological reviews, 1993 - Am Soc Microbiol
The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …

Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection.

CT Wild, DC Shugars, TK Greenwell… - Proceedings of the …, 1994 - National Acad Sciences
To define the role of the human immunodeficiency virus type 1 (HIV-1) envelope proteins in
virus infection, a series of peptides were synthesized based on various regions of the HIV-1 …

[图书][B] HIV and the pathogenesis of AIDS.

JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …

A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated …

K Salzwedel, JT West, E Hunter - Journal of virology, 1999 - Am Soc Microbiol
Mutations were introduced into the ectodomain of the human immunodeficiency virus type 1
(HIV-1) transmembrane envelope glycoprotein, gp41, within a region immediately adjacent …

Virus maturation by budding

H Garoff, R Hewson, DJE Opstelten - Microbiology and molecular …, 1998 - Am Soc Microbiol
Enveloped viruses mature by budding at cellular membranes. It has been generally thought
that this process is driven by interactions between the viral transmembrane proteins and the …

Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes

DH Gabuzda, K Lawrence, E Langhoff… - Journal of …, 1992 - Am Soc Microbiol
The viral infectivity factor gene vif of human immunodeficiency virus type 1 has been shown
to affect the infectivity but not the production of virus particles. In this study, the effect of vif in …

Domains of the human immunodeficiency virus type 1 matrix and gp41 cytoplasmic tail required for envelope incorporation into virions

EO Freed, MA Martin - Journal of virology, 1996 - Am Soc Microbiol
We recently demonstrated that a single amino acid substitution in matrix residue 12 (12LE)
or 30 (30LE) blocks the incorporation of human immunodeficiency virus type 1 (HIV-1) …

Virion incorporation of envelope glycoproteins with long but not short cytoplasmic tails is blocked by specific, single amino acid substitutions in the human …

EO Freed, MA Martin - Journal of virology, 1995 - Am Soc Microbiol
Incorporation of envelope glycoproteins into a budding retrovirus is an essential step in the
formation of an infectious virus particle. By using site-directed mutagenesis, we identified …

Measles viruses with altered envelope protein cytoplasmic tails gain cell fusion competence

T Cathomen, HY Naim, R Cattaneo - Journal of virology, 1998 - Am Soc Microbiol
The cytoplasmic tail of the measles virus (MV) fusion (F) protein is often altered in viruses
which spread through the brain of patients suffering from subacute sclerosing …