2-((2, 6-Dichlorophenyl) amino) benzoic acid (2-DCABA), a potential non-steroidal anti- inflammatory drug and an analog of 2-((2, 6-dimethylphenyl) amino) benzoic acid (HDMPA) …
Addition of methyl group (s) to either or both aromatic rings of fenamic acid (FA) afforded three FA derivatives (1–3), designed to investigate the effect on the polymorphic behavior of …
A series of homologues (1–4) of fenamic acid have been synthesized by varying the length of the linker between the two aromatic rings, and their polymorphism has been investigated …
Flunixin [2-(3-trifluoromethyl-2-methyl-phenylamino)-nicotinic acid, FLX], a potent nonsteroidal anti-inflammatory drug widely used in veterinary medicine, was found to exist in …
Y Tao, X Liu, Y Zhoujin, P Zhou, S Parkin, T Li, J Guo… - …, 2022 - pubs.rsc.org
To probe the effect of substitution on the benzoic acid ring on the polymorphism of phenylaminobenzoic acids, five 3-methyl-2-(phenylamino) benzoic acids (MPABAs) were …
On the basis of crystal engineering, two similar esters of phenyl pyridine-2-carboxylate (I) and phenyl pyrazine-2-carboxylate (II) were designed and synthesized. The compounds …
A series of phenylalkylamino-nicotinic acids (1–4) were synthesized by varying the length of the linker between the pyridine and benzene rings, and their polymorphism was …
Y Liu, M Zhang, D Xu, S Parkin, T Li, C Li… - Crystal Growth & …, 2019 - ACS Publications
To probe the effect of substituent size and isomerization on the polymorphism of fenamic acid (FA) derivatives, we synthesized two FA analogues, namely, 2-(naphthalen-1-ylamino) …
Crystals of the title compound, C12H8Cl2N2O2, were obtained by slow evaporation of an ethanolic solution. An intramolecular amideN—H⋯ O= Clactam hydrogen bond is observed …