Background The widespread use of Immune checkpoint-inhibitors (ICI) has revolutionised
treatment of multiple cancer types. However, selecting patients who may benefit from ICI …

The effect of gut bacteria on the response to immune checkpoint inhibitors (ICIs) has been
studied, but the relationship between fungi and ICI responses is not fully understood. Herein …

The gut microbiota influences anti-tumor immunity and can induce or inhibit response to
immune checkpoint inhibitors (ICIs). Therefore, microbiome features are being studied as …

The lack of multi-omics cancer datasets with extensive follow-up information hinders the
identification of accurate biomarkers of clinical outcome. In this cohort study, we performed …

Simple Summary One of the newest therapies for the treatment of non-small cell lung cancer
is immunotherapy targeting the immune checkpoints PD-1 and PD-L1. Factors are now …

Although more than a decade has passed since the approval of immune checkpoint
inhibitors (ICIs) for the treatment of melanoma and non-small-cell lung, breast and …

The human gut microbiome is an intricate ecosystem with profound implications for host
metabolism, immune function, and neuroendocrine activity. Over the years, studies have …

Gastrointestinal (GI) cancers constitute more than 33% of new cancer cases worldwide and
pose a considerable burden on public health. There exists a growing body of evidence that …

Background In recent years, human microbiome studies have received increasing attention
as this field is considered a potential source for clinical applications. With the advancements …

Recent studies have shown that the microbiome can impact cancer development,
progression, and response to therapies suggesting microbiome-based approaches for …