Conditional deletion of CEACAM1 in hepatic stellate cells causes their activation

HT Muturi, HE Ghadieh, S Asalla, SG Lester… - Molecular …, 2024 - Elsevier
Objectives Hepatic CEACAM1 expression declines with advanced hepatic fibrosis stage in
patients with metabolic dysfunction-associated steatohepatitis (MASH). Global and …

[HTML][HTML] Cell-specific regulation of insulin action and hepatic fibrosis by CEACAM1

BG Aldroubi, JA Najjar, TS Youssef… - … and target organ …, 2024 - pmc.ncbi.nlm.nih.gov
The incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) has
reached an epidemic rise worldwide. The disease is a constellation of a broad range of …

Hepatic GDP-fucose transporter SLC35C1 attenuates cholestatic liver injury and inflammation by inducing CEACAM1 N153 fucosylation

L Zhang, P Xie, M Li, X Zhang, S Fei, N Zhao, L Li… - Hepatology, 2024 - journals.lww.com
Hepatology Publish Ahead of Print DOI:10.1097/HEP.0000000000001003 Page 1 Hepatic
GDP-fucose transporter SLC35C1 attenuates cholestatic liver injury and inflammation by …

Loss of CEACAM1 in hepatocytes causes hepatic fibrosis

S Zaidi, S Asalla, HT Muturi, L Russo… - European Journal of …, 2024 - Wiley Online Library
Background The role of insulin resistance in hepatic fibrosis in Metabolic dysfunction‐
Associated SteatoHepatitis (MASH) remains unclear. Carcinoembryonic Antigen‐related …

Current investigation of carcinoembryonic antigen cell adhesion molecule (CEACAM) biology summary of the 32nd CEA symposium: 20-23 September 2024 …

JM Fleckenstein, SM Najjar… - … journal of clinical …, 2024 - pubmed.ncbi.nlm.nih.gov
Current investigation of carcinoembryonic antigen cell adhesion molecule (CEACAM) biology
summary of the 32nd CEA symposium: 20-23 September 2024. Würzburg, Germany Current …

CEACAM1 Targets ABCA1 to Mediate Atrial Fibrillation via Lipophagy-Dependent Ferroptosis

W Hu, J Zou, Z Li, B Yang, X Ma, R Zhou, J Pu, J Wang… - bioRxiv, 2024 - biorxiv.org
Atrial fibrillation (AF) is one of the most common arrhythmias, imposing a significant burden
on individuals due to its association with cerebrovascular events. The mechanisms …

Conditional deletion of CEACAM1 causes hepatic stellate cell activation

HT Muturi, HE Ghadieh, S Asalla, SG Lester, S Verhulst… - bioRxiv, 2024 - biorxiv.org
Objectives: Hepatic CEACAM1 expression declines with advanced hepatic fibrosis stage in
patients with MASH. Global and hepatocyte-specific deletions of Ceacam1 impair insulin …

Bioinformatics and next generation data analysis reveals the potential role of inflammation in sepsis and its associated complications

B Vastrad, C Vastrad - bioRxiv, 2023 - biorxiv.org
Sepsis is the leading systemic inflammatory response syndrome in worldwide, yet relatively
little is known about the genes and signaling pathways involved in sepsis progression. The …

[引用][C] CEACAM1: Shielding the liver against fibrosis

K Zhang - European Journal of Clinical Investigation, 2024 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD), now renamed as metabolic dysfunction-
associated steatotic liver disease (MASLD), is a precursor or a hepatic manifestation of …