Insights into the structure and function of the hippocampus: implications for the pathophysiology and treatment of autism spectrum disorder

J Long, H Li, Y Liu, X Liao, Z Tang, K Han… - Frontiers in …, 2024 - frontiersin.org
The hippocampus is one of the brain areas affected by autism spectrum disorder (ASD).
Individuals with ASD typically have impairments in hippocampus-dependent learning …

Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice

Y Zhang, W Zheng, M Zhu, H Li, W Ouyang… - Journal of …, 2024 - Soc Neuroscience
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by
persistent deficits in social communication and stereotyped behaviors. Although major …

Taurine inhibits KDM3a production and microglia activation in lipopolysaccharide-treated mice and BV-2 cells

K Liu, R Zhu, H Jiang, B Li, Q Geng, Y Li, J Qi - Molecular and Cellular …, 2022 - Elsevier
Microglia activation has been suggested as the key factor in neuro-inflammation and thus
participates in neurological diseases. Although taurine exhibits anti-inflammatory and neuro …

Amelioration of propionic acid-induced autism spectrum disorder in rats through dapagliflozin: The role of IGF-1/IGFBP-3 and the Nrf2 antioxidant pathway

MA Erdogan, P Nesil, I Altuntas, C Sirin, Y Uyanikgil… - Neuroscience, 2024 - Elsevier
The biological effects of dapagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor,
reveal its antioxidant and anti-inflammatory properties, suggesting therapeutic benefits …

The effects of postnatal erythropoietin and nano‐erythropoietin on behavioral alterations by mediating K‐Cl co‐transporter 2 in the valproic acid‐induced rat model of …

S Haratizadeh, M Ranjbar… - Developmental …, 2023 - Wiley Online Library
In this study, based on the excitatory/inhibitory imbalance theory of autism, the time window
of GABA switch, the role of K‐Cl co‐transporter 2 (KCC2) in adjustment GABA switch, and …

[HTML][HTML] Torasemide improves the propionic acid-induced autism in rats: A histopathological and imaging study

M Doğan, Y Albayrak, O Erbaş - Alpha Psychiatry, 2023 - ncbi.nlm.nih.gov
Objective: Autism spectrum disorder is a neurodevelopmental disease in which impaired
social behaviors, impaired sociality, and restricted and repetitive behaviors are seen …

Astrocyte responses to postnatal erythropoietin and nano-erythropoietin treatments in a valproic acid-induced animal model of autism

S Haratizadeh, M Ranjbar, M Basiri, M Nozari - Journal of Chemical …, 2023 - Elsevier
Background Despite ample evidence of the potential protective effects of erythropoietin
(EPO) on the developing brain, no study has addressed the effects of postnatal EPO on …

[HTML][HTML] SHANK3 mutation and Phelan-Mcdermid syndrome

A Demirezen, O Erbaş - Journal of Experimental and Basic Medical …, 2023 - jebms.org
Abstract The 22q13. 3 deletion syndrome, also known as Phelan-McDermid syndrome
(PMS), has been identified in more than 2200 people worldwide. Globally, there is a delay in …

Demonstration of ameliorating effect of vardenafil through its anti-inflammatory and neuroprotective properties in autism spectrum disorder induced by propionic acid …

B Özkul, FE Urfalı, İH Sever, MF Bozkurt… - International Journal …, 2022 - Taylor & Francis
Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder with
complex etiology. In this study, we aimed to determine the ameliorating effects of vardenafil …

[HTML][HTML] Reparative, Neuroprotective and Anti-neurodegenerative Effects of Granulocyte Colony Stimulating Factor in Radiation-Induced Brain Injury Model

G Gürkan, Ö Atasoy, N Çini, İH Sever… - Journal of Korean …, 2023 - synapse.koreamed.org
Objective This animal model aimed to compare the rat group that received brain irradiation
and did not receive additional treatment (only saline) and the rat group that underwent brain …