Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion

E Eggenhofer, V Benseler, A Kroemer… - Frontiers in …, 2012 - frontiersin.org
Mesenchymal stem cells (MSC) are under investigation as a therapy for a variety of
disorders. Although animal models show long term regenerative and immunomodulatory …

Role of mesenchymal stem cell-derived fibrinolytic factor in tissue regeneration and cancer progression

B Heissig, D Dhahri, S Eiamboonsert, Y Salama… - Cellular and molecular …, 2015 - Springer
Tissue regeneration during wound healing or cancer growth and progression depends on
the establishment of a cellular microenvironment. Mesenchymal stem cells (MSC) are part of …

Allogeneic MSCs and recycled autologous chondrons mixed in a one-stage cartilage cell transplantion: a first-in-man trial in 35 patients

TS de Windt, LA Vonk, ICM Slaper-Cortenbach… - Stem …, 2017 - academic.oup.com
MSCs are known as multipotent mesenchymal stem cells that have been found capable of
differentiating into various lineages including cartilage. However, recent studies suggest …

Cell tracking using 19F magnetic resonance imaging: Technical aspects and challenges towards clinical applications

H Amiri, M Srinivas, A Veltien, MJ van Uden… - European …, 2015 - Springer
Abstract 19 F MRI is emerging as a new imaging technique for cell tracking. It is particularly
attractive because of its potential for direct and precise cell quantification. The most …

[HTML][HTML] Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells

IA Akkouh, T Ueland, L Hansson, E Inderhaug… - Brain, behavior, and …, 2020 - Elsevier
Schizophrenia (SCZ) is a severe mental disorder with a high heritability. Although its
pathophysiology is mainly unknown, dysregulated immune activation and inflammation have …

Micron-sized iron oxide particles for both MRI cell tracking and magnetic fluid hyperthermia treatment

L Dallet, D Stanicki, P Voisin, S Miraux, EJ Ribot - Scientific reports, 2021 - nature.com
Iron oxide particles (IOP) are commonly used for Cellular Magnetic Resonance Imaging
(MRI) and in combination with several treatments, like Magnetic Fluid Hyperthermia (MFH) …

Tracking the fates of iron-labeled tumor cells in vivo using magnetic particle imaging

AV Makela, MA Schott, OC Sehl, JJ Gevaert… - Nanoscale …, 2022 - pubs.rsc.org
The use of imaging to detect and monitor the movement and accumulation of cells in living
subjects can provide significant insights that can improve our understanding of metastasis …

A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia

A Szabo, IA Akkouh, M Vandenberghe… - Translational …, 2021 - nature.com
While neurodevelopmental abnormalities have been associated with schizophrenia (SCZ),
the role of astroglia in disease pathophysiology remains poorly understood. In the present …

Biodegradable, polymer encapsulated, metal oxide particles for MRI‐based cell tracking

EM Shapiro - Magnetic resonance in medicine, 2015 - Wiley Online Library
Metallic particles have shaped the use of magnetic resonance imaging (MRI) for molecular
and cellular imaging. Although these particles have generally been developed for …

Accomplishments and challenges in stem cell imaging in vivo

RJC Bose, RF Mattrey - Drug Discovery Today, 2019 - Elsevier
Highlights•We address the extraordinary progress in stem cell labelling and tracking in
vivo.•We highlight the existing modalities proposed for in vivo stem cell imaging.•We …