The germinal matrix-intraventricular hemorrhage (GM-IVH) is one of the most important
complications of the preterm newborn. Since these children are born at a critical time in …

Abstract Cav1. 2 L-type calcium channels play key roles in long-term synaptic plasticity,
sensory transduction, muscle contraction, and hormone release. De novo mutations in the …

Temperature is one of the most relevant parameters for the regulation of intracellular
processes. Measuring localized subcellular temperature gradients is fundamental for a …

Fine orchestration of excitatory and inhibitory synaptic development is required for normal
brain function, and alterations may cause neurodevelopmental disorders. Using sparse …

Alzheimer's disease (AD), a neurodegenerative disorder characterized by progressive
cognitive decline, is the most common form of dementia. Currently, there is no single test that …

Abstract p140Cap is an adaptor protein involved in assembling multi-protein complexes
regulating several cellular processes. p140Cap acts as a tumor suppressor in breast cancer …

p130Cas/BCAR1 is an adaptor protein devoid of any enzymatic or transcriptional activity,
whose modular structure with various binding motifs, allows the formation of multi-protein …

The oligomeric form of the peptide amyloid beta 42 (Abeta42) contributes to the
development of synaptic abnormalities and cognitive impairments associated with …

Neuroblastoma is the most common extra-cranial pediatric solid tumor, responsible for 13–
15% of pediatric cancer death. Its intrinsic heterogeneity makes it difficult to target for …

Glyphosate (Gly) is a broad-spectrum herbicide responsible for the inhibition of the enzyme
5-enolpyruvylshikimate-3-phosphate synthase known to be expressed exclusively in plants …