Potential of dietary hemp and cannabinoids to modulate immune response to enhance health and performance in animals: opportunities and challenges

F Hassan, C Liu, M Mehboob, RM Bilal… - Frontiers in …, 2023 - frontiersin.org
Cannabinoids are a group of bioactive compounds abundantly present in Cannabis sativa
plant. The active components of cannabis with therapeutic potential are known as …

Cannabinoid CB1 receptors regulate salivation

K Andreis, J Billingsley, K Naimi Shirazi… - Scientific reports, 2022 - nature.com
Saliva serves multiple important functions within the body that we typically take for granted,
such as helping prepare food for swallowing and defense against oral pathogens. Dry …

Anti-obesity effect of the CB2 receptor agonist JWH-015 in diet-induced obese mice

ANA Verty, A Stefanidis, AJ McAinch, DH Hryciw… - PLoS …, 2015 - journals.plos.org
The cannabinoid receptor 2 (CB2) is well known for its immune modulatory role. However,
recent localisation of CB2 receptors in metabolically active tissue suggests that the CB2 …

Prediction of the binding affinities and selectivity for CB1 and CB2 ligands using homology modeling, molecular docking, molecular dynamics simulations, and MM …

B Ji, S Liu, X He, VH Man, XQ Xie… - ACS Chemical …, 2020 - ACS Publications
Cannabinoids are a group of chemical compounds that have been used for thousands of
years due to their psychoactive function and systemic physiological effects. There are at …

Cannabinoid CB2R receptors are upregulated with corneal injury and regulate the course of corneal wound healing

N Murataeva, S Miller, A Dhopeshwarkar… - Experimental eye …, 2019 - Elsevier
CB2R receptors have demonstrated beneficial effects in wound healing in several models.
We therefore investigated a potential role of CB2R receptors in corneal wound healing. We …

[3 + 2]-Annulations of N-Hydroxy Allenylamines with Nitrosoarenes: One-Pot Synthesis of Substituted Indole Products

P Sharma, RS Liu - Organic letters, 2016 - ACS Publications
In the presence of O2 and an IPrCuCl additive (5 mol%),[3+ 2]-annulation reactions of N-
hydroxyaniline with nitrosobenzenes in cold toluene form isoxazolidin-5-ol derivatives …

[HTML][HTML] Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein

C Xu, DJ Hermes, B Nwanguma, IR Jacobs… - Molecular and Cellular …, 2017 - Elsevier
In the era of combined antiretroviral therapy (cART), human immunodeficiency virus type 1
(HIV-1) is considered a chronic disease that specifically targets the brain and causes HIV-1 …

CB2 receptor agonism reverses MK-801-induced disruptions of prepulse inhibition in mice

R Khella, JL Short, DT Malone - Psychopharmacology, 2014 - Springer
Rationale Whilst cannabinoid CB 2 receptors were thought to exist predominantly in immune
cells in the periphery, the recent discovery of CB 2 receptors in the brain has led to an …

The endocannabinoid system—a target for the treatment of LUTS?

P Hedlund, C Gratzke - Nature Reviews Urology, 2016 - nature.com
Lower urinary tract symptoms (LUTS) are common in all age groups and both sexes,
resulting in tremendous personal suffering and a substantial burden to society …

Revisiting cannabinoid receptor 2 expression and function in murine retina

J Borowska-Fielding, N Murataeva, B Smith… - …, 2018 - Elsevier
The cannabinoid receptor CB2 plays a significant role in the regulation of immune function
whereas neuronal expression remains a subject of contention. Multiple studies have …