[HTML][HTML] Immunogenic cell death: a step ahead of autophagy in cancer therapy

G Gupta, K Borglum, H Chen - Journal of cancer immunology, 2021 - ncbi.nlm.nih.gov
Immunogenic cell death (ICD) plays a major role in providing long lasting protective
antitumor immunity by the chronic exposure of damage associated molecular patterns …

[HTML][HTML] Association of survivin splice variants with prognosis and treatment of breast cancer

A Pavlidou, C Kroupis, K Dimas - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
The purpose of this study was the overview of current knowledge regarding the use of
survivin and its isoforms in prognosis and treatment of breast cancer. An advanced search of …

FOXM1 targets XIAP and Survivin to modulate breast cancer survival and chemoresistance

GN de Moraes, D Delbue, KL Silva, MC Robaina… - Cellular signalling, 2015 - Elsevier
Drug resistance is a major hurdle for successful treatment of breast cancer, the leading
cause of deaths in women throughout the world. The FOXM1 transcription factor is a potent …

Metabolomic identification of anticancer metabolites of Australian propolis and proteomic elucidation of its synergistic mechanisms with doxorubicin in the MCF7 cells

MA Alsherbiny, DJ Bhuyan, I Radwan… - International Journal of …, 2021 - mdpi.com
The combination of natural products with standard chemotherapeutic agents offers a
promising strategy to enhance the efficacy or reduce the side effects of standard …

Sulforaphane metabolites reduce resistance to paclitaxel via microtubule disruption

Y Wang, Y Zhou, Z Zheng, J Li, Y Yan, W Wu - Cell death & disease, 2018 - nature.com
Long treatment with paclitaxel (PTX) might increase resistance and side-effects causing a
failure in cancer chemotherapy. Here we uncovered that either sulforaphane-cysteine (SFN …

Liposome-coated nano doxorubicin induces apoptosis on oral squamous cell carcinoma CAL-27 cells

ES Abd El-Hamid, AM Gamal-Eldeen… - Archives of oral biology, 2019 - Elsevier
Objective This study aims to investigate the apoptotic effect of Doxorubicin and its nano-
formulated form (Doxil) on oral squamous cell carcinoma CAL-27 cells. Design Cell viability …

High-fidelity and simultaneous sensing of endogenous mutant and wild p53 proteins for precise cancer diagnosis and drug screening

F Yang, X Li, R Yuan, Y Xiang - Analytical Chemistry, 2021 - ACS Publications
The simultaneous sensing of endogenous wild and mutant proteins plays a critical role in
disease diagnosis and drug screening, and this remains a major current challenge. Here …

[HTML][HTML] XIAP underlies apoptosis resistance of renal cell carcinoma cells

WZ Yang, H Zhou, Y Yan - Molecular medicine reports, 2018 - spandidos-publications.com
X‑linked inhibitor of apoptosis (XIAP), a key member of the inhibitors of apoptosis protein
family, can inhibit apoptosis by directly binding to the initiator caspase‑9,‑3 and‑7, thereby …

Doxorubicin-conjugated iron oxide nanoparticles synthesized by laser pyrolysis: in vitro study on human breast cancer cells

II Lungu, S Nistorescu, MA Badea, AM Petre, AM Udrea… - Polymers, 2020 - mdpi.com
Even today, breast cancer remains a global public problem, with a high mortality rate among
women. Nanoparticle (NP) based systems are developed to enhance drug delivery …

Short and long-term effects of the exposure of breast cancer cell lines to different ratios of free or co-encapsulated liposomal paclitaxel and doxorubicin

MS Franco, MC Roque, MC Oliveira - Pharmaceutics, 2019 - mdpi.com
Background: Associating paclitaxel (PTX) to doxorubicin (DXR) is one of the main
chemotherapy strategies for breast cancer (BC) management. Protocols currently available …