PTH receptor signalling, osteocytes and bone disease induced by diabetes mellitus
Basic, translational and clinical research over the past few decades has provided new
understanding on the mechanisms by which activation of the receptor of parathyroid …
understanding on the mechanisms by which activation of the receptor of parathyroid …
Micropetrosis: Osteocyte Lacunar Mineralization in Aging and Disease
P Milovanovic, B Busse - Current Osteoporosis Reports, 2023 - Springer
Abstract Purpose of Review As the importance of osteocytes for bone mineral homeostasis
is increasingly recognized, there is growing interest in osteocyte cell death as a relevant …
is increasingly recognized, there is growing interest in osteocyte cell death as a relevant …
Bone intrinsic material and compositional properties in postmenopausal women diagnosed with long-term Type-1 diabetes
W Qian, S Gamsjaeger, EP Paschalis, LA Graeff-Armas… - Bone, 2023 - Elsevier
The incidence of diabetes mellitus and the associated complications are growing worldwide,
affecting the patients' quality of life and exerting a considerable burden on health systems …
affecting the patients' quality of life and exerting a considerable burden on health systems …
Bone remodeling and responsiveness to mechanical stimuli in individuals with type 1 diabetes mellitus
M Walle, A Duseja, DE Whittier, T Vilaca… - Journal of Bone and …, 2024 - academic.oup.com
Type 1 diabetes mellitus (T1DM) has been linked to increased osteocyte apoptosis, local
accumulation of mineralized lacunar spaces, and microdamage suggesting an impairment …
accumulation of mineralized lacunar spaces, and microdamage suggesting an impairment …
Lower microhardness along with less heterogeneous mineralization in the femoral neck of individuals with type 2 diabetes mellitus indicates higher fracture risk
A Cirovic, FN Schmidt, M Vujacic, P Sihota… - JBMR plus, 2024 - academic.oup.com
There is still limited understanding of the microstructural reasons for the higher susceptibility
to fractures in individuals with type 2 diabetes mellitus (T2DM). In this study, we examined …
to fractures in individuals with type 2 diabetes mellitus (T2DM). In this study, we examined …
Quantitative ultrasound imaging reveals distinct fracture-associated differences in tibial intracortical pore morphology and viscoelastic properties in aged individuals …
C Dehnen, A Galindo, P Hoff, O Palme… - Frontiers in …, 2024 - frontiersin.org
Introduction Diabetes mellitus (DM) is a chronic metabolic disorder that increases fragility
fracture risk. Conventional DXA-based areal bone mineral density (aBMD) assessments …
fracture risk. Conventional DXA-based areal bone mineral density (aBMD) assessments …
[HTML][HTML] Pronounced cortical porosity and sex-specific patterns of increased bone and osteocyte lacunar mineralization characterize the human distal fibula with aging
RN Hering, S von Kroge, J Delsmann, A Simon… - Bone, 2024 - Elsevier
The high occurrence of distal fibula fractures among older women suggests a potential link
to impaired bone health. Here we used a multiscale imaging approach to investigate the …
to impaired bone health. Here we used a multiscale imaging approach to investigate the …
Enzymatic and Non-enzymatic Collagen Cross-Links and Fracture Occurrence in Type 1 Diabetes Patients
EP Paschalis, S Gamsjaeger, LA Graeff-Armas… - Calcified Tissue …, 2024 - Springer
Increased fracture risk in type 1 diabetes (T1D) patients is not fully captured by bone mineral
density (BMD) by DXA. Advanced glycation end-products (AGEs) have been implicated in …
density (BMD) by DXA. Advanced glycation end-products (AGEs) have been implicated in …
[HTML][HTML] Herb couplet medicines (Erxian) protect osteoblasts from high glucose-induced damage by reducing cell apoptosis in diabetic osteoporosis: A network …
X Zhou, M Li, M Zhang, Y Zhang - European Journal of Integrative Medicine, 2024 - Elsevier
Abstract Introduction Traditional Chinese medicine (TCM) has unique advantages in treating
diabetic osteoporosis (DOP). This study aimed to explore the mechanisms underlying the …
diabetic osteoporosis (DOP). This study aimed to explore the mechanisms underlying the …