Evaluation methods and strategies to improve compression characteristics of pharmaceutical powders

M Ren, H Xu, X Zhang, J Guan, S Mao - Journal of Drug Delivery Science …, 2024 - Elsevier
Although tablets have been the most commonly used oral solid dosage forms, there are still
challenges with capping, lamination, and punch sticking throughout the manufacturing …

Worsened punch sticking by external lubrication with magnesium stearate

T Xiang, CC Sun - International journal of pharmaceutics, 2024 - Elsevier
External lubrication of tooling with magnesium stearate (MgSt) is a common strategy to
eliminate punch sticking when compressing powders with a high sticking propensity, such …

A Commentary on Co-Processed API as a Promising Approach to Improve Sustainability for the Pharmaceutical Industry

L Schenck, B Risteen, LM Johnson, A Koynov… - Journal of …, 2024 - Elsevier
Pharmaceutical products represent a meaningful target for sustainability improvement and
emissions reduction. It is proposed here that rethinking the standard, and often linear …

Uncovering the mechanism of Tenofovir amibufenamide fumarate punch sticking by combining direct compression experiment and computational simulation

C Zhao, X Wang, Y Liu, X Qin, W Chen, J Zhang… - International Journal of …, 2024 - Elsevier
Punch sticking during tablet manufacturing is a prevalent issue for many active
pharmaceutical ingredients (APIs) encountered by the pharmaceutical industry. Tenofovir …

Enhancement of material attributes of poorly compressible metformin hydrochloride through coprocessing with hydroxypropyl cellulose (HPC-L) using coprecipitation …

K Chaturvedi, P Pongkulapa, X Ding, HS Shah… - AAPS Open, 2023 - Springer
Coprocessing involves integration of multiple substances to improve the physical, chemical,
mechanical, and biopharmaceutical properties of a material. Coprocessing is a promising …

Regulatory Considerations for Stability Studies of Co-Processed Active Pharmaceutical Ingredient

RK Orr, T Rawalpally, LS Gorka, LR Bonaga… - The AAPS Journal, 2024 - Springer
A co-processed active pharmaceutical ingredient (CP API) is the combination of an active
pharmaceutical ingredient (API) with non-active component (s). This technology has been …

Efficient development of high drug loaded posaconazole tablets enabled by amorphous solid dispersion

T Xiang, S Song, RA Siegel, CC Sun - RSC Pharmaceutics, 2025 - pubs.rsc.org
Determining the upper limits of drug loading in amorphous solid dispersion (ASD) with
sufficient physical stability and release performance is critical for developing ASD-enabled …

[PDF][PDF] Adsorption Onto Solid Carriers Enhances the Flow Properties and Release of Alpinia galanga Ethanolic Extract.

NA Karim Khan, IM Ali - Malaysian Journal of Medicine & Health …, 2024 - medic.upm.edu.my
Introduction: There are many natural products which have the potential of ameliorating the
deterioration in health due to aging. Some of the natural products are in the form of ethanol …

Magnio Aliuminio Metasilikato Įtaka Tablečių Su Augaliniais Ekstraktais Kokybei

M Kaminskaitė - 2024 - search.proquest.com
Tyrimo tikslas–pagaminti tabletes, naudojant daugiafunkcinę medžiagą magnio aliuminio
metasilikatą ir atlikti tablečių kokybės vertinimą. Tyrimo uždaviniai: Remiantis mokslinės …