Review of optical coherence tomography in oncology

J Wang, Y Xu, SA Boppart - Journal of biomedical optics, 2017 - spiedigitallibrary.org
The application of optical coherence tomography (OCT) in the field of oncology has been
prospering over the past decade. OCT imaging has been used to image a broad spectrum of …

Imaging approaches for monitoring three‐dimensional cell and tissue culture systems

G Hilzenrat, ET Gill, SL McArthur - Journal of Biophotonics, 2022 - Wiley Online Library
The past decade has seen an increasing demand for more complex, reproducible and
physiologically relevant tissue cultures that can mimic the structural and biological features …

Optimizing supercontinuum spectro-temporal properties by leveraging machine learning towards multi-photon microscopy

VT Hoang, Y Boussafa, L Sader, S Février… - Frontiers in …, 2022 - frontiersin.org
Multi-photon microscopy has played a significant role in biological imaging since it allows to
observe living tissues with improved penetration depth and excellent sectioning effect. Multi …

High-speed imaging of transient metabolic dynamics using two-photon fluorescence lifetime imaging microscopy

AJ Bower, J Li, EJ Chaney, M Marjanovic… - Optica, 2018 - opg.optica.org
Two-photon fluorescence lifetime imaging microscopy (2P-FLIM) of autofluorescent
metabolic coenzymes has been widely used to investigate energetic perturbations in living …

Digital staining through the application of deep neural networks to multi-modal multi-photon microscopy

N Borhani, AJ Bower, SA Boppart… - Biomedical optics …, 2019 - opg.optica.org
Deep neural networks have been used to map multi-modal, multi-photon microscopy
measurements of a label-free tissue sample to its corresponding histologically stained …

Tracking metabolic dynamics of apoptosis with high-speed two-photon fluorescence lifetime imaging microscopy

AJ Bower, JE Sorrells, J Li, M Marjanovic… - Biomedical Optics …, 2019 - opg.optica.org
Programmed cell death, or apoptosis, is an essential process in development and
homeostasis, and disruptions in associated pathways are responsible for a wide variety of …

Label‐free in vivo cellular‐level detection and imaging of apoptosis

AJ Bower, M Marjanovic, Y Zhao, J Li… - Journal of …, 2017 - Wiley Online Library
Cell death plays a critical role in health and homeostasis as well as in the pathogenesis and
treatment of a broad spectrum of diseases and can be broadly divided into two main …

Assessing the severity of psoriasis through multivariate analysis of optical images from non-lesional skin

M Žurauskas, R Barkalifa, A Alex, M Marjanovic… - Scientific reports, 2020 - nature.com
Patients with psoriasis represent a heterogeneous population with individualized disease
expression. Psoriasis can be monitored through gold standard histopathology of biopsy …

Fluorescence lifetime shifts of NAD (P) H during apoptosis measured by time‐resolved flow cytometry

F Alturkistany, K Nichani, KD Houston… - Cytometry Part …, 2019 - Wiley Online Library
Autofluorescence from the intracellular metabolite, NAD (P) H, is a biomarker that is widely
used and known to reliably screen and report metabolic activity as well as metabolic …

Characterization and identification of cell death dynamics by quantitative phase imaging

HC Hsieh, PT Lin, KB Sung - Journal of biomedical optics, 2022 - spiedigitallibrary.org
Significance: Investigating cell death dynamics at the single-cell level plays an essential role
in biological research. Quantitative phase imaging (QPI), a label-free method without …