Multiphasic Continuous‐Flow Reactors for Handling Gaseous Reagents in Organic Synthesis: Enhancing Efficiency and Safety in Chemical Processes

AAH Laporte, TM Masson, SDA Zondag… - Angewandte …, 2024 - Wiley Online Library
The use of reactive gaseous reagents for the production of active pharmaceutical
ingredients (APIs) remains a scientific challenge due to safety and efficiency limitations. The …

Application of reactor engineering concepts in continuous flow chemistry: a review

NC Neyt, DL Riley - Reaction Chemistry & Engineering, 2021 - pubs.rsc.org
The adoption of flow technology for the manufacture of chemical entities, and in particular
pharmaceuticals, has seen rapid growth over the past two decades with the technology now …

Concurrent oxidation–reduction reactions in a single system using a low-plasma phenomenon: excellent catalytic performance and stability in the hydrogenation …

W Al Zoubi, AW Allaf, B Assfour… - ACS Applied Materials & …, 2022 - ACS Publications
The catalytic activity and stability of metal nanocatalysts toward agglomeration and
detachment during their preparation on a support surface are major challenges in practical …

Aerobic oxidation of alcohols using a slurry loop membrane reactor

B Venezia, A Gavriilidis - Green Chemistry, 2023 - pubs.rsc.org
The use of molecular oxygen is unquestionably the green path to the selective oxidation of
alcohols to aldehyde and ketones. However, this reaction class poses safety problems …

Toward Continuous‐Flow Hyperpolarisation of Metabolites via Heterogenous Catalysis, Side‐Arm‐Hydrogenation, and Membrane Dissolution of Parahydrogen

WG Hale, TY Zhao, D Choi, MJ Ferrer, B Song… - …, 2021 - Wiley Online Library
Side‐arm hydrogenation (SAH) by homogeneous catalysis has extended the reach of the
parahydrogen enhanced NMR technique to key metabolites such as pyruvate. However …

Towards Heterogeneous Catalysis: A Review on Recent Advances of Depositing Nanocatalysts in Continuous–Flow Microreactors

H Feng, Y Zhang, J Liu, D Liu - Molecules, 2022 - mdpi.com
As a promising technology, microreactors have been regarded as a potential candidate for
heterogeneous catalytic reactions as they inherently allow the superior advantages of …

Ethylene and cyclohexane co-production in the fixed-bed catalytic membrane reactor: Experimental study and modeling optimization

MHK Darvanjooghi, M Malakootikhah… - Journal of Membrane …, 2022 - Elsevier
In this study, a fixed-bed catalytic membrane reactor was used for the production of ethylene
and cyclohexane from ethane and benzene. A two-dimensional non-isothermal …

Copper-Catalyzed Continuous-Flow Transfer Hydrogenation of Nitroarenes to Anilines: A Scalable and Reliable Protocol

K Martina, MJ Moran, M Manzoli… - … Process Research & …, 2023 - ACS Publications
A robust supported catalyst that is made up of copper nanoparticles on Celite has been
successfully prepared for the selective transfer hydrogenation of aromatic nitrobenzenes to …

[HTML][HTML] 3D-printed packed bed reactor for continuous catalytic hydrogenation of nitroaromatic compounds

P Cyganowski, W Tylus, S Kinas, P Jamróz - Chemical Engineering and …, 2025 - Elsevier
Aromatic amines (AAMs) are essential compounds for producing a wide range of industrial
and pharmaceutical products. However, traditional synthesis methods using nitroaromatic …

An Automated Computer‐Vision “Bubble‐Counting” Technique to Characterise CO2 Dissolution into an Acetonitrile Flow Stream in a Teflon AF‐2400 Tube‐in‐Tube …

M O'Brien, R Moraru - ChemPlusChem, 2023 - Wiley Online Library
A Teflon AF‐2400 based tube‐in‐tube device was used to generate flow streams of CO2 in
acetonitrile and a computer‐vision based 'bubble counting'technique was used to estimate …