Sepsis and septic shock are characterized by life-threatening organ dysfunction caused by a
dysregulated host response to infection. The liver has a central role during sepsis, and is …

Patients with cirrhosis and portal hypertension often develop complications from a variety of
organ systems leading to a multiple organ failure. The combination of liver failure and portal …

Hepatorenal syndrome (HRS) carries a high short‐term mortality in patients with cirrhosis
and acute on chronic liver failure (ACLF). Terlipressin and noradrenaline are routinely used …

Patients with cirrhosis have a high risk of bacterial infections. Bacterial infections induce
systemic inflammation that may lead to organ failure and acute‐on‐chronic liver failure …

Patients with cirrhosis are susceptible to develop infections because of immune dysfunction,
changes in microbiome and increase in bacterial translocation from the gut to systemic …

Ascites represents the most common decompensating event in patients with liver cirrhosis.
The appearance of ascites is strongly related to portal hypertension, which leads to …

Sepsis is a dysregulated immune response to an infection that leads to organ dysfunction.
Sepsis-associated organ dysfunction involves multiple inflammatory mechanisms and …

Systemic infections is one of the major causes of mortality worldwide, and a shortage of drug
approaches applied for the rapid and necessary treatment contribute to increase the levels …

The present study aimed to examine the expression and function of the metastasis-
associated lung adenocarcinoma transcript 1 (MALAT1)/microRNA (miR)-146a/nuclear …

Liver failure in the context of acute (ALF) and acute on chronic liver failure (ACLF) is
associated with high mortality in the absence of a liver transplant. For decades, therapeutic …