[HTML][HTML] Nanotherapeutic strategy against glioblastoma using enzyme inhibitors

R Thiruvengadam, BO Dareowolabi, EY Moon… - Biomedicine & …, 2024 - Elsevier
Glioblastoma is the most aggressive brain cancer and thus patients with glioblastoma have
a severely low 5-year survival rate (< 5%). Glioblastoma damages neural centers, causing …

Contemporary strategies in glioblastoma therapy: Recent developments and innovations

M Khan, M Nasim, M Feizy, R Parveen, A Gull, S Khan… - Neuroscience, 2024 - Elsevier
Glioblastoma multiforme (GBM) represents one of the most prevailing and aggressive
primary brain tumors among adults. Despite advances in therapeutic approaches, the …

Effects of lomerizine and its metabolite on glioblastoma cells

Y Uemichi, M Mabuchi, N Tsuchiya… - Anticancer …, 2024 - ar.iiarjournals.org
Background/Aim: Glioblastoma is an incurable cancer with limited treatment options and a
low survival rate. Temozolomide is the standard marketed small-molecule agent for …

Pentraxin 3: A Main Driver of Inflammation and Immune System Dysfunction in the Tumor Microenvironment of Glioblastoma

SA Scuderi, A Ardizzone, AE Salako, G Pantò… - Cancers, 2024 - mdpi.com
Simple Summary Brain tumors, including glioblastoma (GB), pose a significant health
concern globally, with high mortality rates despite current therapies. Pentraxin 3 (PTX3) is a …

[HTML][HTML] Glioma Stem Cells: GPRC5A as a Novel Predictive Biomarker and Therapeutic Target Associated with Mesenchymal and Stemness Features

SS Aghamiri, R Amin - Applied Sciences, 2024 - mdpi.com
Glioblastoma multiforme (GBM) represents the deadliest form of brain cancer, characterized
by complex interactions within its microenvironment. Despite the understanding of GBM …

[HTML][HTML] Sesquiterpene Lactones as Promising Anti-Glioblastoma Drug Candidates Exerting Complex Effects on Glioblastoma Cell Viability and Proneural …

AV Markov, AD Moralev, KV Odarenko - Biomedicines, 2025 - mdpi.com
Glioblastoma is one of the most aggressive brain cancers, characterized by active infiltrative
growth and high resistance to radiotherapy and chemotherapy. Sesquiterpene triterpenoids …

A Comprehensive review on exploring Thymoquinone as novel therapeutic molecule for clinical management of Glioblastoma Multiforme

S Trivedi, U Hussain, R Agade, V Belgamwar - … Research-Natural Products, 2024 - Elsevier
Glioblastoma Multiforme (GBM) is a deadly and aggressive brain cancer with rapid
progression and resistance to conventional treatments. Patients suffering from GBM have a …

[HTML][HTML] COSMC-Regulated O-Glycosylation: A Bioinformatics-Driven Biomarker Identification for Stratifying Glioblastoma Stem Cell Subtypes

SS Aghamiri, R Amin - Kinases and Phosphatases, 2024 - mdpi.com
Glioblastoma stem cells (GSCs) are key drivers of relapse, metastasis, and therapy
resistance in glioblastoma due to their adaptability and diversity, which make them …

Combined use of radiomics and artificial neural networks for the three‐dimensional automatic segmentation of glioblastoma multiforme

AM de los Reyes, VH Lord, ME Buemi… - Expert …, 2024 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most prevalent and aggressive primary brain tumour
that has the worst prognosis in adults. Currently, the automatic segmentation of this kind of …

INVOLVEMENT OF THE TEN-ELEVEN TRANSLOCATION (TET) ENZYMES AND 5-HYDROXYMETHYLCYTOSINE (5HMC) IN THE DNA DAMAGE RESPONSE AND …

M Malloy - 2024 - jscholarship.library.jhu.edu
Gliomas are the most common type of primary brain cancer and glioblastomas (GBM) are
the most common and lethal subtype of gliomas. GBM patients face a poor prognosis due to …