Breaking the loop: oxytocin as a potential treatment for drug addiction

IS McGregor, MT Bowen - Hormones and behavior, 2012 - Elsevier
Drug use typically occurs within a social context, and social factors play an important role in
the initiation, maintenance and recovery from addictions. There is now accumulating …

Alcohol, stress hormones, and the prefrontal cortex: a proposed pathway to the dark side of addiction

YL Lu, HN Richardson - Neuroscience, 2014 - Elsevier
Chronic exposure to alcohol produces changes in the prefrontal cortex that are thought to
contribute to the development and maintenance of alcoholism. A large body of literature …

Adolescent rearing conditions influence the relationship between initial anxiety‐like behavior and ethanol drinking in male Long Evans rats

AM Chappell, E Carter, BA McCool… - Alcoholism: Clinical …, 2013 - Wiley Online Library
Background Rodent studies have demonstrated that adolescent social isolation results in
many behavioral perturbations, including increases in anxiety‐like behaviors. Socially …

Activation of μ-opioid receptors in the dorsal striatum is necessary for adult social attachment in monogamous prairie voles

JP Burkett, LL Spiegel, K Inoue, AZ Murphy… - …, 2011 - nature.com
Despite significant evidence that opioids are involved in attachment by mediating social
reward and motivation, the role of opioids in the formation of adult social attachments has …

In the company of others: social factors alter acute alcohol effects

MG Kirkpatrick, H De Wit - Psychopharmacology, 2013 - Springer
Rationale Alcohol is usually consumed in social contexts. However, the drug has been
studied mainly under socially isolated conditions, and our understanding of how social …

The glucagon-like peptide 1 receptor agonist Exendin-4 decreases relapse-like drinking in socially housed mice

M Thomsen, D Dencker, G Wörtwein, P Weikop… - Pharmacology …, 2017 - Elsevier
Abstract Glucagon-like peptide-1 (GLP-1) is a gut peptide that regulates food intake and
glucose metabolism. GLP-1 is also produced and released in the brain, and GLP-1 …

Ethanol Intake Under Social Circumstances or Alone in S prague–D awley Rats: Impact of Age, Sex, Social Activity, and Social Anxiety‐Like Behavior

EI Varlinskaya, EM Truxell… - Alcoholism: Clinical and …, 2015 - Wiley Online Library
Background In human adolescents, heavy drinking is often predicted by high sociability in
males and high social anxiety in females. This study assessed the impact of baseline levels …

The impact of taste preference-related gene polymorphisms on alcohol consumption behavior: A systematic review

AAM Kurshed, R Ádány, J Diószegi - International Journal of Molecular …, 2022 - mdpi.com
Unhealthy alcohol consumption is recognized as a leading contributory factor to mortality
and disability. In addition to other factors, taste sensation also mediates alcohol intake. The …

[HTML][HTML] Neurogenetics and nutrigenomics of neuro-nutrient therapy for reward deficiency syndrome (RDS): clinical ramifications as a function of molecular …

K Blum, M Oscar-Berman, E Stuller… - Journal of addiction …, 2012 - ncbi.nlm.nih.gov
In accord with the new definition of addiction published by American Society of Addiction
Medicine (ASAM) it is well-known that individuals who present to a treatment center involved …

Excessive alcohol consumption after exposure to two types of chronic social stress: intermittent episodes vs. continuous exposure in C57BL/6J mice with a history of …

KA Miczek, N Akdilek, VMM Ferreira, E Kenneally… - …, 2022 - Springer
Rationale The attraction to alcohol can be greatly increased when it is consumed in a social
context. While pro-social interactions can potentiate voluntary alcohol drinking under some …