Calcium (Ca2+) sparks are the elementary events of excitation–contraction coupling, yet
they are not explicitly represented in human ventricular myocyte models. A stochastic …

Cardiovascular disease is the leading cause of death worldwide due in a large part to
arrhythmia. In order to understand how calcium dynamics play a role in arrhythmogenesis …

Studying cardiac diseases using human tissue is proven difficult and limited, even in
optimized clinical conditions. Computer simulation studies have been continuously …