CRISPR-based tools for fighting rare diseases

Q Li, Y Gao, H Wang - Life, 2022 - mdpi.com
Rare diseases affect the life of a tremendous number of people globally. The CRISPR-Cas
system emerged as a powerful genome engineering tool and has facilitated the …

[HTML][HTML] Adenoviral Vectors for Gene Therapy of Hereditary Diseases

A Muravyeva, S Smirnikhina - Biology, 2024 - mdpi.com
Adenoviral vectors (AdVs) are effective vectors for gene therapy due to their broad tropism,
high capacity, and high transduction efficiency, which makes them actively used as oncolytic …

Popularizing recombinant baculovirus-derived onebac system for laboratory production of all recombinant adeno-associated virus vector serotypes

Y Wu, Z Han, M Duan, L Jiang, T Tian… - Current Gene …, 2021 - ingentaconnect.com
Background: Recombinant adeno-associated virus (rAAV) has been widely used as an
efficient transgenic vector in biomedical research, as well as gene therapy. Serotype …

Popularizing recombinant baculovirus-derived OneBac system for scaling-up production of all recombinant adeno-associated virus vector serotypes

Y Wu, Z Han, M Duan, L Jiang, T Tian, D Jin, Q Wang… - bioRxiv, 2020 - biorxiv.org
Recombinant adeno-associated virus (rAAV) has been widely used as an efficient
transgenic vector in biomedical research, as well as gene therapy. Serotype-associated …

Methods and materials for producing recombinant viruses in eukaryotic microalgae

BK Kaspar - US Patent 10,907,130, 2021 - Google Patents
The present invention is directed to methods and materials for producing recombinant
viruses. In particular, methods and materials are provided for producing recombinant viruses …

[引用][C] Hemophilia Therapy by Factor IX Knock-in Into Anticoagulant Antithrombin III Using Adeno-Associated Virus and Lipid Nanoparticle

이정현 - 2022 - 서울대학교대학원